OBJECTIVE: The aim of this study was to determine which T stages of incidental gallbladder carcinoma (IGBC) actually benefit from an early reresection (ERR). BACKGROUND: The IGBC is a carcinoma first detected by the pathologist. The indication for the cholecystectomy was a benign disease. The indication for an ERR is debated in the literature, and different recommendations are often drawn based on data collected from only small groups. METHODS: A register was founded in 1997 to prospectively record all IGBCs in Germany. All the patients who had a reresection in this study were treated according to the German Guidelines of Surgery and Oncology. This study analyzes 439 cases of IGBC. RESULTS: There was a significant benefit for the 85 of 200 T2 patients who did have an ERR. There was no benefit though for the 32 of 85 T3 patients who did have an ERR. There is a significantly better survival rate for T2 patients with negative lymph nodes, and there is a trend for better survival for T3 patients with negative lymph nodes. CONCLUSION: An ERR should be highly recommended for patients with IGBC in the T2 stage, because it improves their survival positive. Without an ERR, it is almost impossible to definitively determine the nodal status or to obtain exact staging for estimating the prognosis.
OBJECTIVE: The aim of this study was to determine which T stages of incidental gallbladder carcinoma (IGBC) actually benefit from an early reresection (ERR). BACKGROUND: The IGBC is a carcinoma first detected by the pathologist. The indication for the cholecystectomy was a benign disease. The indication for an ERR is debated in the literature, and different recommendations are often drawn based on data collected from only small groups. METHODS: A register was founded in 1997 to prospectively record all IGBCs in Germany. All the patients who had a reresection in this study were treated according to the German Guidelines of Surgery and Oncology. This study analyzes 439 cases of IGBC. RESULTS: There was a significant benefit for the 85 of 200 T2 patients who did have an ERR. There was no benefit though for the 32 of 85 T3 patients who did have an ERR. There is a significantly better survival rate for T2 patients with negative lymph nodes, and there is a trend for better survival for T3 patients with negative lymph nodes. CONCLUSION: An ERR should be highly recommended for patients with IGBC in the T2 stage, because it improves their survival positive. Without an ERR, it is almost impossible to definitively determine the nodal status or to obtain exact staging for estimating the prognosis.
Authors: Javier C Lendoire; Luis Gil; Fernando Duek; Carlos Quarin; Verónica Garay; Gabriel Raffin; Marcelo Rivaldi; Oks Alejandra; Oscar Imventarza Journal: HPB (Oxford) Date: 2012-06-08 Impact factor: 3.647
Authors: T Tsirlis; F Ausania; S A White; J J French; B C Jaques; R M Charnley; D M Manas Journal: Ann R Coll Surg Engl Date: 2015-03 Impact factor: 1.891
Authors: Junichi Shindoh; Xabier de Aretxabala; Thomas A Aloia; Juan Carlos Roa; Ivan Roa; Giuseppe Zimmitti; Milind Javle; Claudius Conrad; Dipen M Maru; Taku Aoki; Luca Vigano; Dario Ribero; Norihiro Kokudo; Lorenzo Capussotti; Jean-Nicolas Vauthey Journal: Ann Surg Date: 2015-04 Impact factor: 12.969