Literature DB >> 18156634

Direct observation and adherence to tuberculosis treatment in Chongqing, China: a descriptive study.

Daiyu Hu1, Xiaoyun Liu, Jing Chen, Yang Wang, Tao Wang, Wei Zeng, Helen Smith, Paul Garner.   

Abstract

INTRODUCTION: China has an estimated 5 million people with tuberculosis (TB). Official policy is that treatment of all patients is directly observed by health workers; completion rates are reported to be in excess of 90%, and drugs should be supplied for free. However, some research suggests there is a gap between the official policies and practice.
METHODS: Survey of TB patients in four counties of one municipality; record assessment at one TB centre; patient and village doctor in-depth interviews.
RESULTS: Sixteen per cent (64/401) reported being directly observed every time they took treatment; less than 5% of TB patients (17/401) were observed by health staff. Overall, 12.5% (50/401) reported they had not taken any TB drugs in the previous week, but this varied between the four counties (range 6.2 to 21.7%). We used survival analysis with medical records at one centre: 74.1% of new patients collected their drugs for their sixth month of treatment, and 50.3% attended the final visit at 6 months. Qualitative research indicated direct observation is neither well understood nor thought to be necessary, and that patients reported being charged expensive fees for ancillary treatments, such as liver protection drugs.
CONCLUSION: In China, direct observation is not well implemented and may not be a feasible policy option. Official completion rates are higher than we found in this study. The concept of free treatment has become blurred, with charges for additional tests and drugs, especially liver protection drugs. The government is already actively tackling these issues, and involvement of managers and others in this process will be helpful.

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Year:  2008        PMID: 18156634     DOI: 10.1093/heapol/czm038

Source DB:  PubMed          Journal:  Health Policy Plan        ISSN: 0268-1080            Impact factor:   3.344


  24 in total

1.  Doubts about DOTS.

Authors:  G R Davies; S B Squire
Journal:  BMJ       Date:  2008-02-04

2.  Factors associated with low cure rate of tuberculosis in remote poor areas of Shaanxi Province, China: a case control study.

Authors:  Xianqin Ai; Ke Men; Liujia Guo; Tianhua Zhang; Yan Zhao; Xiaolu Sun; Hongwei Zhang; Guangxue He; Marieke J van der Werf; Susan van den Hof
Journal:  BMC Public Health       Date:  2010-03-07       Impact factor: 3.295

Review 3.  Patient medical costs for tuberculosis treatment and impact on adherence in China: a systematic review.

Authors:  Qian Long; Helen Smith; Tuohong Zhang; Shenglan Tang; Paul Garner
Journal:  BMC Public Health       Date:  2011-05-26       Impact factor: 3.295

Review 4.  Prevalence of drug-resistant tuberculosis in mainland China: systematic review and meta-analysis.

Authors:  Yu Yang; Xiangwei Li; Feng Zhou; Qi Jin; Lei Gao
Journal:  PLoS One       Date:  2011-06-03       Impact factor: 3.240

5.  Treatment adherence among sputum smear-positive pulmonary tuberculosis patients in mountainous areas in China.

Authors:  Song Yao; Wen-Hui Huang; Susan van den Hof; Shu-Min Yang; Xiao-Lin Wang; Wei Chen; Xue-Hui Fang; Hai-Feng Pan
Journal:  BMC Health Serv Res       Date:  2011-12-16       Impact factor: 2.655

6.  Risk factors for non-cure among new sputum smear positive tuberculosis patients treated in tuberculosis dispensaries in Yunnan, China.

Authors:  Hua Jianzhao; Susan van den Hof; Xu Lin; Qiu Yubang; Hou Jinglong; Marieke J van der Werf
Journal:  BMC Health Serv Res       Date:  2011-05-11       Impact factor: 2.655

7.  Development and validation of a tuberculosis medication adherence scale.

Authors:  Xiaoxv Yin; Xiaochen Tu; Yeqing Tong; Rui Yang; Yunxia Wang; Shiyi Cao; Hong Fan; Feng Wang; Yanhong Gong; Ping Yin; Zuxun Lu
Journal:  PLoS One       Date:  2012-12-12       Impact factor: 3.240

8.  Pulmonary tuberculosis incidence and risk factors in rural areas of China: a cohort study.

Authors:  Wei Chen; Wen Shu; Min Wang; Yongchun Hou; Yinyin Xia; Weiguo Xu; Liqiong Bai; Shaofa Nie; Shiming Cheng; Yihua Xu
Journal:  PLoS One       Date:  2013-03-12       Impact factor: 3.240

9.  China's biggest, most neglected health challenge: Non-communicable diseases.

Authors:  Shenglan Tang; John Ehiri; Qian Long
Journal:  Infect Dis Poverty       Date:  2013-04-05       Impact factor: 4.520

10.  Language and rigour in qualitative research: problems and principles in analyzing data collected in Mandarin.

Authors:  Helen J Smith; Jing Chen; Xiaoyun Liu
Journal:  BMC Med Res Methodol       Date:  2008-07-10       Impact factor: 4.615

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