Literature DB >> 18155710

Separation of amino acid enantiomers VIA chiral derivatization and non-chiral gas chromatography.

Marylène Bertrand1, Annie Chabin, André Brack, Frances Westall.   

Abstract

Two GC-MS methods for the enantioselective separation of the 20 proteinogenic amino acids are compared. Ethyl chloroformate and 2-chloropropanol were used to derivatize amino acid enantiomers. The diastereomers formed were separated on a non-chiral column by capillary gas chromatography. The separation performances were compared to those obtained when using non-chiral derivatization on a chiral column.

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Year:  2007        PMID: 18155710     DOI: 10.1016/j.chroma.2007.12.004

Source DB:  PubMed          Journal:  J Chromatogr A        ISSN: 0021-9673            Impact factor:   4.759


  1 in total

Review 1.  Chiral secondary amino acids, their importance, and methods of analysis.

Authors:  Helena Zahradníčková; Stanislav Opekar; Lucie Řimnáčová; Petr Šimek; Martin Moos
Journal:  Amino Acids       Date:  2022-02-21       Impact factor: 3.520

  1 in total

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