Literature DB >> 1815513

[Synthesis and properties of DNA-duplexes, containing 9-(1'-hydroxy-2'-(hydroxymethyl)ethoxy)methylguanine].

E A Romanova, L G Kuznetsova, E A Kubareva, A V Tsytovich, I N Merenkova, T S Oretskaia, E S Gromova, Z A Shabarova.   

Abstract

Phosphoramidite derivative of 9-[1'-hydroxy-2'-(hydroxymethyl)ethoxy]methylguanine (glG) is synthesized which allows one to introduce point modifications in any position of the chemically prepared oligonucleotide chain. Oligonucleotides with 5'-terminal glG can be used in chemical ligation promoted by cyanogen bromide. The modified oligonucleotide duplexes were characterized by melting curves and CD spectra.

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Year:  1991        PMID： 1815513

Source DB:  PubMed          Journal:  Bioorg Khim        ISSN： 0132-3423


  2 in total

1.  Cleavage of synthetic substrates containing non-nucleotide inserts by restriction endonucleases. Change in the cleavage specificity of endonuclease SsoII.

Authors:  E A Kubareva; O V Petrauskene; A S Karyagina; V N Tashlitsky; I I Nikolskaya; E S Gromova
Journal:  Nucleic Acids Res       Date:  1992-09-11       Impact factor: 16.971

2.  DNA duplexes with reactive dialdehyde groups as novel reagents for cross-linking to restriction- modification enzymes.

Authors:  M G Brevnov; O M Gritsenko; S N Mikhailov; E V Efimtseva; B S Ermolinsky; A Van Aerschot; P Herdewijn; A V Repyk; E S Gromova
Journal:  Nucleic Acids Res       Date:  1997-08-15       Impact factor: 16.971
  2 in total

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