Literature DB >> 1814682

Effect of dichloroacetate on oxidative removal of lactate in mice after supramaximal exercise.

H Hatta1, R Soma, Y Atomi.   

Abstract

1. The effect of dichloroacetate (DCA), which activates substrate oxidation on oxidative removal of lactate in mice after supramaximal exercise was investigated. 2. DCA significantly decreased the blood lactate concentration and increased the oxidative removal of lactate during prolonged exercise. 3. No significant differences were found in the removal of the blood lactate concentration, in oxidative removal of lactate after supramaximal exercise. 4. It is concluded that DCA administration which activates lactate oxidation during exercise does not activate lactate oxidation in mice after supramaximal exercise.

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Year:  1991        PMID: 1814682     DOI: 10.1016/0305-0491(91)90220-8

Source DB:  PubMed          Journal:  Comp Biochem Physiol B        ISSN: 0305-0491


  2 in total

1.  The effects of endurance training and thiamine supplementation on anti-fatigue during exercise.

Authors:  Sung-Keun Choi; Seung-Hui Baek; Seung-Wook Choi
Journal:  J Exerc Nutrition Biochem       Date:  2013-11-17

2.  Effects of decreased lactate accumulation after dichloroacetate administration on exercise training-induced mitochondrial adaptations in mouse skeletal muscle.

Authors:  Daisuke Hoshino; Yuki Tamura; Hiroyuki Masuda; Yutaka Matsunaga; Hideo Hatta
Journal:  Physiol Rep       Date:  2015-09
  2 in total

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