Literature DB >> 1814013

Isolation of IgGT from hyperimmune horse anti-snake venom serum: its protective ability.

I Fernandes1, H A Takehara, I Mota.   

Abstract

Hyperimmune horse anti-bothropic serum, used in serum therapy, was analyzed for its IgGT content and protective ability. IgGT was isolated through a combination of salt-mediated hydrophobic chromatography and protein A affinity chromatography. The chromatographic fractions obtained were analyzed with regard to their isotype content and protective ability. The results suggest that the protective ability of hyperimmune anti-venom serum is located mainly in the IgGT subclass.

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Year:  1991        PMID： 1814013     DOI： 10.1016/0041-0101(91)90124-a

Source DB:  PubMed          Journal:  Toxicon        ISSN： 0041-0101            Impact factor:   3.033


  6 in total

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3.  Snake F(ab')2 antivenom from hyperimmunized horse: pharmacokinetics following intravenous and intramuscular administrations in rabbits.

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Review 4.  Engineering venom's toxin-neutralizing antibody fragments and its therapeutic potential.

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Journal:  Toxins (Basel)       Date:  2014-08-21       Impact factor: 4.546

5.  Quality-Related Properties of Equine Immunoglobulins Purified by Different Approaches.

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Journal:  Toxins (Basel)       Date:  2020-12-14       Impact factor: 4.546

6.  A Heterologous Multiepitope DNA Prime/Recombinant Protein Boost Immunisation Strategy for the Development of an Antiserum against Micrurus corallinus (Coral Snake) Venom.

Authors:  Henrique Roman Ramos; Inácio de Loiola M Junqueira-de-Azevedo; Juliana Branco Novo; Karen Castro; Clara Guerra Duarte; Ricardo A Machado-de-Ávila; Carlos Chavez-Olortegui; Paulo Lee Ho
Journal:  PLoS Negl Trop Dis       Date:  2016-03-03
  6 in total

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