Literature DB >> 18112778

Timed intravenous infusion of metrazol and strychnine for testing anticonvulsant drugs.

M J ORLOFF, H L WILLIAMS, C C PFEIFFER.   

Abstract

Entities:  

Keywords:  CONVULSIONS/experimental; EPILEPSY/experimental; METRAZOL/effects; STRYCHNINE/effects

Mesh:

Substances:

Year:  1949        PMID: 18112778     DOI: 10.3181/00379727-70-16891

Source DB:  PubMed          Journal:  Proc Soc Exp Biol Med        ISSN: 0037-9727


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  15 in total

1.  Reversibility of a facilitatory action of reserpine on the central nervous system, by methylamphetamine.

Authors:  W KOBINGER
Journal:  Experientia       Date:  1958-09-15

2.  Novel, broad-spectrum anticonvulsants containing a sulfamide group: pharmacological properties of (S)-N-[(6-chloro-2,3-dihydrobenzo[1,4]dioxin-2-yl)methyl]sulfamide (JNJ-26489112).

Authors:  David F McComsey; Virginia L Smith-Swintosky; Michael H Parker; Douglas E Brenneman; Ewa Malatynska; H Steve White; Brian D Klein; Karen S Wilcox; Michael E Milewski; Mark Herb; Michael F A Finley; Yi Liu; Mary Lou Lubin; Ning Qin; Allen B Reitz; Bruce E Maryanoff
Journal:  J Med Chem       Date:  2013-11-11       Impact factor: 7.446

3.  Normal cerebellar development but susceptibility to seizures in mice lacking G protein-coupled, inwardly rectifying K+ channel GIRK2.

Authors:  S Signorini; Y J Liao; S A Duncan; L Y Jan; M Stoffel
Journal:  Proc Natl Acad Sci U S A       Date:  1997-02-04       Impact factor: 11.205

4.  A new derivative of valproic acid amide possesses a broad-spectrum antiseizure profile and unique activity against status epilepticus and organophosphate neuronal damage.

Authors:  H Steve White; Anitha B Alex; Amanda Pollock; Naama Hen; Tawfeeq Shekh-Ahmad; Karen S Wilcox; John H McDonough; James P Stables; Dan Kaufmann; Boris Yagen; Meir Bialer
Journal:  Epilepsia       Date:  2011-12-09       Impact factor: 5.864

5.  Effects of ascorbate on a dopaminergic response: apomorphine-induced modification of pentylenetetrazol-induced seizures in mice.

Authors:  R E Wilcox; W H Riffee; C P Goldman; R K Young
Journal:  Psychopharmacology (Berl)       Date:  1984       Impact factor: 4.530

Review 6.  The early identification of anticonvulsant activity: role of the maximal electroshock and subcutaneous pentylenetetrazol seizure models.

Authors:  H S White; M Johnson; H H Wolf; H J Kupferberg
Journal:  Ital J Neurol Sci       Date:  1995 Feb-Mar

7.  The effects of chronic administration and withdrawal of (+)-amphetamine on seizure threshold and endogenous catecholamine concentrations and their rates of biosynthesis in mice.

Authors:  W H Riffee; M C Gerald
Journal:  Psychopharmacology (Berl)       Date:  1977-01-31       Impact factor: 4.530

8.  Pharmacokinetic modeling of the anticonvulsant response of oxazepam in rats using the pentylenetetrazol threshold concentration as pharmacodynamic measure.

Authors:  J Dingemanse; F A Sollie; D D Breimer; M Danhof
Journal:  J Pharmacokinet Biopharm       Date:  1988-04

9.  Effects of apomorphine and piribedil on pentylenetetrazol-induced seizures in mice.

Authors:  W H Riffee; R E Wilcox; C P Goldman; R V Smith
Journal:  Psychopharmacology (Berl)       Date:  1981       Impact factor: 4.530

10.  HAP1 Modulates Epileptic Seizures by Regulating GABAAR Function in Patients with Temporal Lobe Epilepsy and in the PTZ-Induced Epileptic Model.

Authors:  Rong Li; Bing Wu; Miaoqing He; Peng Zhang; Qinbin Zhang; Jing Deng; Jinxian Yuan; Yangmei Chen
Journal:  Neurochem Res       Date:  2020-05-17       Impact factor: 3.996

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