Literature DB >> 181063

Effect of adrenergic agonists on phosphatidylinositol labelling in heart and aorta.

E G Lapetina, P A Briley, E De Robertis.   

Abstract

(1) The metabolism of phosphatidylinositol has been investigated in heart fragments and aorta slices incubated with adrenergic agonists. (2) Noradrenaline and isoprenaline had no stimulatory effect on 32Pi incorporation into phosphatidylinositol in cat and guinea-pig hearts. (3) Incorporation of 32Pi into phosphatidylinositol was enhanced by noradrenaline and methoxamine in cat aorta. (4) This information is consistent with the idea that the enhanced phosphatidylinositol turnover produced during adrenergic stimulation is mediated through alpha-adrenergic receptors and not through beta-adrenoceptors.

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Year:  1976        PMID： 181063     DOI： 10.1016/0005-2760(76)90226-5

Source DB:  PubMed          Journal:  Biochim Biophys Acta        ISSN： 0006-3002


  4 in total

1.  Lipid metabolism of developing central nervous tissues in organotypic cultures. III. Ganglionic control of glycerolipids and fatty acids in cortex grey matter.

Authors:  M Giesing; F Zilliken
Journal:  Neurochem Res       Date:  1980-03       Impact factor: 3.996

2.  Stimulation of inorganic-phosphate incorporation into phosphatidylinositol in rat thoracic aorta mediated through V1-vasopressin receptors.

Authors:  A P Takhar; C J Kirk
Journal:  Biochem J       Date:  1981-01-15       Impact factor: 3.857

3.  Inositol trisphosphate-induced calcium release and contraction in vascular smooth muscle.

Authors:  A V Somlyo; M Bond; A P Somlyo; A Scarpa
Journal:  Proc Natl Acad Sci U S A       Date:  1985-08       Impact factor: 11.205

4.  Phosphorylation of phospholipids in isolated guinea pig hearts stimulated with isoprenaline.

Authors:  G Jakab; S T Rapundalo; R J Solaro; E G Kranias
Journal:  Biochem J       Date:  1988-04-01       Impact factor: 3.857
  4 in total

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