Literature DB >> 1810200

Lack of evidence for a saturable tetracycline transport system in Staphylococcus aureus.

I Chopra1, S Ismail, B Oliva.   

Abstract

Previous studies on tetracycline transport into Staphylococcus aureus identified a high-affinity, saturable uptake system for the antibiotic (Km, 4.76 microM) (B.L. Hutchings, Biochim. Biophys. Acta 174:734-738, 1969). However, the earlier results could not be confirmed using conditions that permitted energy-dependent, concentrative uptake of tetracycline. Kinetic artifacts introduced by inappropriate washing procedures may explain the previous results.

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Year:  1991        PMID： 1810200      PMCID： PMC245447          DOI： 10.1128/AAC.35.12.2643

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  10 in total

1.  Uptake of tetracycline by Escherichia coli is not mediated by the sodium dependent glutamate transport system.

Authors:  I Chopra; S Ismail
Journal:  J Antimicrob Chemother       Date:  1990-11       Impact factor: 5.790

2.  Two transport systems for tetracycline in sensitive Escherichia coli: critical role for an initial rapid uptake system insensitive to energy inhibitors.

Authors:  L McMurry; S B Levy
Journal:  Antimicrob Agents Chemother       Date:  1978-08       Impact factor: 5.191

3.  Properties of a cryptic high-frequency transducing phage in Staphylococcus aureus.

Authors:  R Novick
Journal:  Virology       Date:  1967-09       Impact factor: 3.616

4.  Amino acid transport systems in Escherichia coli K-12.

Authors:  J R Piperno; D L Oxender
Journal:  J Biol Chem       Date:  1968-11-25       Impact factor: 5.157

5.  Tetracycline transport in Staphylococcus aureus H.

Authors:  B L Hutchings
Journal:  Biochim Biophys Acta       Date:  1969-02-18

Review 6.  Molecular mechanisms involved in the transport of antibiotics into bacteria.

Authors:  I Chopra
Journal:  Parasitology       Date:  1988       Impact factor: 3.234

7.  Transport of the lipophilic analog minocycline differs from that of tetracycline in susceptible and resistant Escherichia coli strains.

Authors:  L M McMurry; J C Cullinane; S B Levy
Journal:  Antimicrob Agents Chemother       Date:  1982-11       Impact factor: 5.191

8.  Energetics of tetracycline transport into Escherichia coli.

Authors:  M C Smith; I Chopra
Journal:  Antimicrob Agents Chemother       Date:  1984-04       Impact factor: 5.191

9.  Tetracycline diffusion through phospholipid bilayers and binding to phospholipids.

Authors:  M Argast; C F Beck
Journal:  Antimicrob Agents Chemother       Date:  1984-08       Impact factor: 5.191

10.  Tetracycline uptake by susceptible Escherichia coli cells.

Authors:  M Argast; C F Beck
Journal:  Arch Microbiol       Date:  1985-04       Impact factor: 2.552
  10 in total

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