Literature DB >> 18097889

Anterograde transsynaptic tracing in the murine somatosensory system using Pseudorabies virus (PrV): a "live-cell"-tracing tool for analysis of identified neurons in vitro.

Markus Rothermel1, Nicole Schöbel, Nils Damann, Barbara G Klupp, Thomas C Mettenleiter, Hanns Hatt, Christian H Wetzel.   

Abstract

The Pseudorabies virus (PrV) strain Bartha is widely used as a tool for retrograde transneuronal tracing in mammals. Traced neurons can be identified in cell culture allowing the analysis of their physiological features ("live-cell"-tracing). Compared to PrV-Bartha, PrV-Kaplan is known for higher virulence and transsynaptic spread in both retrograde and anterograde direction. Herein we assess the authors assess PrV-Kaplan for transsynaptic anterograde "live-cell"-tracing. Following intranasal application in mice, labelled trigeminal and brainstem neurons could be identified in vitro. Detailed electrophysiological analysis indicated that viral infection did not affect neuronal properties, making PrV-Kaplan eligible for functional analysis of identified neurons within somatosensory systems.

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Year:  2007        PMID： 18097889     DOI： 10.1080/13550280701586419

Source DB:  PubMed          Journal:  J Neurovirol        ISSN： 1355-0284            Impact factor:   2.643


  21 in total

1.  Virus-assisted mapping of neural inputs to a feeding center in the hypothalamus.

Authors:  J DeFalco; M Tomishima; H Liu; C Zhao; X Cai; J D Marth; L Enquist; J M Friedman
Journal:  Science       Date:  2001-03-30       Impact factor: 47.728

2.  Changes in excitability induced by herpes simplex viruses in rat dorsal root ganglion neurons.

Authors:  M L Mayer; M H James; R J Russell; J S Kelly; C A Pasternak
Journal:  J Neurosci       Date:  1986-02       Impact factor: 6.167

3.  Activity of cardiorespiratory networks revealed by transsynaptic virus expressing GFP.

Authors:  M Irnaten; R A Neff; J Wang; A D Loewy; T C Mettenleiter; D Mendelowitz
Journal:  J Neurophysiol       Date:  2001-01       Impact factor: 2.714

4.  "Cold" fiber population innervating palmar and digital skin of the monkey: responses to cooling pulses.

Authors:  I Darian-Smith; K O Johnson; R Dykes
Journal:  J Neurophysiol       Date:  1973-03       Impact factor: 2.714

5.  Orexins induce increased excitability and synchronisation of rat sympathetic preganglionic neurones.

Authors:  Marco van den Top; Matthew F Nolan; Kevin Lee; Peter J Richardson; Ruud M Buijs; Ceri H Davies; David Spanswick
Journal:  J Physiol       Date:  2003-04-17       Impact factor: 5.182

6.  Characterization of the central nervous system innervation of the rat spleen using viral transneuronal tracing.

Authors:  G Cano; A F Sved; L Rinaman; B S Rabin; J P Card
Journal:  J Comp Neurol       Date:  2001-10-08       Impact factor: 3.215

Review 7.  Exploiting circuit-specific spread of pseudorabies virus in the central nervous system: insights to pathogenesis and circuit tracers.

Authors:  L W Enquist
Journal:  J Infect Dis       Date:  2002-12-01       Impact factor: 5.226

8.  Pseudorabies virus expressing enhanced green fluorescent protein: A tool for in vitro electrophysiological analysis of transsynaptically labeled neurons in identified central nervous system circuits.

Authors:  B N Smith; B W Banfield; C A Smeraski; C L Wilcox; F E Dudek; L W Enquist; G E Pickard
Journal:  Proc Natl Acad Sci U S A       Date:  2000-08-01       Impact factor: 11.205

9.  Definition of neuronal circuitry controlling the activity of phrenic and abdominal motoneurons in the ferret using recombinant strains of pseudorabies virus.

Authors:  I Billig; J M Foris; L W Enquist; J P Card; B J Yates
Journal:  J Neurosci       Date:  2000-10-01       Impact factor: 6.167

10.  Intracochlear injection of pseudorabies virus labels descending auditory and monoaminerg projections to olivocochlear cells in guinea pig.

Authors:  Miklós Horváth; Ottó Ribári; Gábor Répássy; Ida E Tóth; Zsolt Boldogkõi; Miklós Palkovits
Journal:  Eur J Neurosci       Date:  2003-09       Impact factor: 3.386
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  8 in total

1.  Activation of oral trigeminal neurons by fatty acids is dependent upon intracellular calcium.

Authors:  Tian Yu; Bhavik P Shah; Dane R Hansen; MieJung Park-York; Timothy A Gilbertson
Journal:  Pflugers Arch       Date:  2012-05-30       Impact factor: 3.657

Review 2.  Emerging role of viral vectors for circuit-specific gene interrogation and manipulation in rodent brain.

Authors:  Erika Sarno; Alfred J Robison
Journal:  Pharmacol Biochem Behav       Date:  2018-04-27       Impact factor: 3.533

Review 3.  Transneuronal tracing to map connectivity in injured and transplanted spinal networks.

Authors:  Tara A Fortino; Margo L Randelman; Adam A Hall; Jasbir Singh; David C Bloom; Esteban Engel; Daniel J Hoh; Shaoping Hou; Lyandysha V Zholudeva; Michael A Lane
Journal:  Exp Neurol       Date:  2022-01-25       Impact factor: 5.620

4.  Pseudorabies virus infection alters neuronal activity and connectivity in vitro.

Authors:  Kelly M McCarthy; David W Tank; Lynn W Enquist
Journal:  PLoS Pathog       Date:  2009-10-30       Impact factor: 6.823

5.  Advanced tracing tools: functional neuronal expression of virally encoded fluorescent calcium indicator proteins.

Authors:  Markus Rothermel; Daniela Brunert; Barbara G Klupp; Matthias Luebbert; Thomas C Mettenleiter; Hanns Hatt
Journal:  J Neurovirol       Date:  2009-09       Impact factor: 2.643

6.  Trigeminal ganglion neurons of mice show intracellular chloride accumulation and chloride-dependent amplification of capsaicin-induced responses.

Authors:  Nicole Schöbel; Debbie Radtke; Matthias Lübbert; Günter Gisselmann; Ramona Lehmann; Annika Cichy; Benjamin S P Schreiner; Janine Altmüller; Alan C Spector; Jennifer Spehr; Hanns Hatt; Christian H Wetzel
Journal:  PLoS One       Date:  2012-11-08       Impact factor: 3.240

7.  The Possible Neuronal Mechanism of Acupuncture: Morphological Evidence of the Neuronal Connection between Groin A-Shi Point and Uterus.

Authors:  Chun-Yen Chen; Rey-Shyong Chern; Ming-Huei Liao; Yung-Hsien Chang; Jung-Yu C Hsu; Chi-Hsien Chien
Journal:  Evid Based Complement Alternat Med       Date:  2013-02-28       Impact factor: 2.629

8.  Entry of herpes simplex virus type 1 (HSV-1) into the distal axons of trigeminal neurons favors the onset of nonproductive, silent infection.

Authors:  Wali Hafezi; Eva U Lorentzen; Bodo R Eing; Marcus Müller; Nicholas J C King; Barbara Klupp; Thomas C Mettenleiter; Joachim E Kühn
Journal:  PLoS Pathog       Date:  2012-05-10       Impact factor: 6.823
  8 in total

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