Literature DB >> 18097235

Combination antiretroviral therapy failure and HIV super-infection.

Daniela Bezemer1, Ard van Sighem, Frank de Wolf, Marion Cornelissen, Antoinette C van der Kuyl, Suzanne Jurriaans, Lia van der Hoek, Maria Prins, Roel A Coutinho, Vladimir V Lukashov.   

Abstract

In addition to development or selection of resistance, failure to continuously suppress HIV-1 production while still using initially effective combination antiretroviral therapy (cART) may result from super-infection with a drug-resistant strain. Both transmission of drug resistant HIV and super-infection have been demonstrated. We analysed HIV pol genes obtained before start of initially successful cART and during failure while still on cART in 101 patients. Difference in precART and cART failure sequences were explained by evolution and not by super-infection.

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Year:  2008        PMID: 18097235     DOI: 10.1097/QAD.0b013e3282f37489

Source DB:  PubMed          Journal:  AIDS        ISSN: 0269-9370            Impact factor:   4.177


  6 in total

Review 1.  Immunological and virological characteristics of human immunodeficiency virus type 1 superinfection: implications in vaccine design.

Authors:  Yang Gao; Wen Tian; Xiaoxu Han; Feng Gao
Journal:  Front Med       Date:  2017-11-23       Impact factor: 4.592

2.  HIV Type 1 transmission networks among men having sex with men and heterosexuals in Kenya.

Authors:  Daniela Bezemer; Nuno Rodrigues Faria; Amin Hassan; Raph L Hamers; Gaudensia Mutua; Omu Anzala; Kishor Mandaliya; Patricia Cane; James A Berkley; Tobias F Rinke de Wit; Carole Wallis; Susan M Graham; Matthew A Price; Roel A Coutinho; Eduard J Sanders
Journal:  AIDS Res Hum Retroviruses       Date:  2013-09-17       Impact factor: 2.205

3.  Multiple HIV-1 infections with evidence of recombination in heterosexual partnerships in a low risk Rural Clinical Cohort in Uganda.

Authors:  Deogratius Ssemwanga; Frederick Lyagoba; Nicaise Ndembi; Billy N Mayanja; Natasha Larke; Shuyi Wang; Joshua Baalwa; Carolyn Williamson; Heiner Grosskurth; Pontiano Kaleebu
Journal:  Virology       Date:  2011-01-15       Impact factor: 3.616

4.  An RNAi in silico approach to find an optimal shRNA cocktail against HIV-1.

Authors:  María C Méndez-Ortega; Silvia Restrepo; Luis M Rodríguez-R; Iván Pérez; Juan C Mendoza; Andrés P Martínez; Roberto Sierra; Gloria J Rey-Benito
Journal:  Virol J       Date:  2010-12-20       Impact factor: 4.099

5.  First line antiretroviral treatment failure and associated factors among people living with HIV in northwest Ethiopia.

Authors:  Andualem Genet; Zewdie Mekonnen; Endalew Yizengaw; Daniel Mekonnen
Journal:  Afr Health Sci       Date:  2021-03       Impact factor: 0.927

6.  Behavioral and molecular tracing of risky sexual contacts in a sample of Chinese HIV-infected men who have sex with men.

Authors:  Haijiang Lin; Na He; Sujuan Zhou; Yingying Ding; Danhong Qiu; Tiejun Zhang; Frank Y Wong
Journal:  Am J Epidemiol       Date:  2013-01-24       Impact factor: 4.897

  6 in total

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