| Literature DB >> 18095699 |
Christopher W Barfoot1, Alan R Burns, Michael G Edwards, Martin N Kenworthy, Mahmood Ahmed, Stephen E Shanahan, Richard J K Taylor.
Abstract
The first synthetic route to the tricyclic core of the dictyosphaeric acids has been established starting from readily available (S)-(-)-4-(tert-butyldimethylsilyloxy)cyclohexenone and involving 9 steps, including a ring-closing metathesis to produce a 13-membered macrolactone, and a doubly tethered intramolecular Michael addition.Entities:
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Year: 2007 PMID： 18095699 DOI： 10.1021/ol702887e
Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005