Literature DB >> 18094997

Thymoma with ganglioneuroblastomatous component: case report.

Kenji Kashiwabara1, Hayato Ikota, Shigebumi Tanaka, Chie Ohta, Toshiki Yajima, Hideki Endoh, Ei Yamaki, Hiroyuki Kuwano, Takashi Nakajima.   

Abstract

A mediastinal tumor in a 49-year-old woman with myasthenia gravis is reported. The tumor was well-demarcated and located in the supero-anterior mediastinum. Microscopically, the tumor consisted of thymic and neuroblastic tumor components, the latter of which consisted of immature and maturing neuronal cells, abundant neuropils, and Schwannian stroma. The two components intermingled with each other inside the tumor capsule. The tumor was diagnosed as thymoma with a ganglioneuroblastomatous component. The coexistence of epithelial and neuronal tissues in the thymic neoplasm is extremely rare.

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Year:  2008        PMID: 18094997     DOI: 10.1007/s00428-007-0544-y

Source DB:  PubMed          Journal:  Virchows Arch        ISSN: 0945-6317            Impact factor:   4.064


  25 in total

1.  Thymic carcinosarcoma associated with a spindle cell thymoma: an immunohistochemical study.

Authors:  D Suarez Vilela; J S Salas Valien; M A Gonzalez Moran; F Izquierdo Garcia; J R Riera Velasco
Journal:  Histopathology       Date:  1992-09       Impact factor: 5.087

2.  Neuroendocrine differentiation in thymic epithelial tumors with special reference to thymic carcinoma and atypical thymoma.

Authors:  T Hishima; M Fukayama; Y Hayashi; T Fujii; K Arai; Y Shiozawa; N Funata; M Koike
Journal:  Hum Pathol       Date:  1998-04       Impact factor: 3.466

Review 3.  A case of sarcomatoid carcinoma of the thymus.

Authors:  M Nishimura; T Kodama; H Nishiyama; Y Nishiwaki; T Yokose; Y Shimosato
Journal:  Pathol Int       Date:  1997-04       Impact factor: 2.534

4.  Ganglioneuroblastoma of the thymus: an adult case with the syndrome of inappropriate secretion of antidiuretic hormone.

Authors:  Y Asada; K Marutsuka; T Mitsukawa; T Kuribayashi; S Taniguchi; A Sumiyoshi
Journal:  Hum Pathol       Date:  1996-05       Impact factor: 3.466

5.  Terminology and morphologic criteria of neuroblastic tumors: recommendations by the International Neuroblastoma Pathology Committee.

Authors:  H Shimada; I M Ambros; L P Dehner; J Hata; V V Joshi; B Roald
Journal:  Cancer       Date:  1999-07-15       Impact factor: 6.860

6.  Neuroendocrine differentiation is a common feature of thymic carcinoma.

Authors:  L Lauriola; R A Erlandson; J Rosai
Journal:  Am J Surg Pathol       Date:  1998-09       Impact factor: 6.394

7.  Ectopic hamartomatous thymoma: clinicopathologic, immunohistochemical, and histogenetic considerations in four new cases.

Authors:  J F Fetsch; S W Weiss
Journal:  Hum Pathol       Date:  1990-06       Impact factor: 3.466

8.  Thymic sarcomatoid carcinoma with skeletal muscle differentiation: report of two cases, one with cytogenetic analysis.

Authors:  T Eimoto; M Kitaoka; H Ogawa; H Niwa; T Murase; H Tateyama; H Inagaki; T Soji; H J Wang
Journal:  Histopathology       Date:  2002-01       Impact factor: 5.087

9.  Adult ganglioneuroblastoma of the anterior mediastinum.

Authors:  Y Nagashima; Y Miyagi; Y Tanaka; M Miyashita; S Shigematsu; I Aoki; Y Nakatani; K Misugi
Journal:  Pathol Res Pract       Date:  1997       Impact factor: 3.250

10.  Thymic carcinoma with focal neuroblastoma differentiation.

Authors:  A Alguacil-Garcia; W C Halliday
Journal:  Am J Surg Pathol       Date:  1987-06       Impact factor: 6.394

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