Literature DB >> 18094939

Regression of severe corneal stromal neovascularization with topical cyclosporine 0.05% after penetrating keratoplasty for fungal corneal ulcer.

Baris Sonmez1, Umit Beden, Dilek Erkan.   

Abstract

PURPOSE: To report regression of corneal stromal neovascularizations with the use of topical cyclosporine 0.05% in a corneal transplant patient performed for fungal corneal ulcer.
DESIGN: Case report.
METHODS: A 14-year-old boy treated for fungal corneal ulceration developed 360 degrees corneal stromal neovascularization peroperatively. Topical cyclosporine 0.05% was used to decrease the risk of rejection.
RESULTS: The neovascularizations regressed totally within 2 months and no signs of graft rejection were present at 6 months follow up.
CONCLUSION: Topical cyclosporine 0.05% may result in regression of stromal corneal neovascularizations and help to reduce the risk of graft rejection in selected cases.

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Year:  2007        PMID: 18094939     DOI: 10.1007/s10792-007-9180-4

Source DB:  PubMed          Journal:  Int Ophthalmol        ISSN: 0165-5701            Impact factor:   2.031


  5 in total

1.  Prevention and treatment of corneal graft rejection: current practice patterns (2004).

Authors:  J Bradley Randleman; R Doyle Stulting
Journal:  Cornea       Date:  2006-04       Impact factor: 2.651

2.  Treatment of HSV-1 stromal keratitis with topical cyclosporin A: a pilot study.

Authors:  A Heiligenhaus; K P Steuhl
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  1999-05       Impact factor: 3.117

3.  Topical cyclosporin A in the management of therapeutic keratoplasty for mycotic keratitis.

Authors:  Henry D Perry; Sima J Doshi; Eric D Donnenfeld; Grace S Bai
Journal:  Cornea       Date:  2002-03       Impact factor: 2.651

4.  Cellular events in the normal and inflamed cornea.

Authors:  Koh-Hei Sonoda; Shintaro Nakao; Takahiro Nakamura; Toru Oshima; Hong Qiao; Toshio Hisatomi; Shigeru Kinoshita; Tatsuro Ishibashi
Journal:  Cornea       Date:  2005-11       Impact factor: 2.651

5.  Selective inhibition of vascular endothelial growth factor-mediated angiogenesis by cyclosporin A: roles of the nuclear factor of activated T cells and cyclooxygenase 2.

Authors:  G L Hernández; O V Volpert; M A Iñiguez; E Lorenzo; S Martínez-Martínez; R Grau; M Fresno; J M Redondo
Journal:  J Exp Med       Date:  2001-03-05       Impact factor: 14.307

  5 in total
  5 in total

Review 1.  Clinical correlates of common corneal neovascular diseases: a literature review.

Authors:  Nizar Saleh Abdelfattah; Mohamed Amgad; Amira A Zayed; Hamdy Salem; Ahmed E Elkhanany; Heba Hussein; Nawal Abd El-Baky
Journal:  Int J Ophthalmol       Date:  2015-02-18       Impact factor: 1.779

2.  Inhibitory effects of regorafenib, a multiple tyrosine kinase inhibitor, on corneal neovascularization.

Authors:  Halil Ibrahim Onder; Mesut Erdurmus; Yasin Yücel Bucak; Hüseyin Simavli; Murat Oktay; Ahmet Sahap Kukner
Journal:  Int J Ophthalmol       Date:  2014-04-18       Impact factor: 1.779

3.  Role of Frequency Doubled Nd: Yag Laser in Treatment of Corneal Neovascularisation.

Authors:  Jitendra Kumar; Aakanksha Gehra; Naveen Sirohi
Journal:  J Clin Diagn Res       Date:  2016-04-01

Review 4.  Novel aspects of corneal angiogenic and lymphangiogenic privilege.

Authors:  David Ellenberg; Dimitri T Azar; Joelle A Hallak; Faisal Tobaigy; Kyu Yeon Han; Sandeep Jain; Zhongjun Zhou; Jin-Hong Chang
Journal:  Prog Retin Eye Res       Date:  2010-01-25       Impact factor: 21.198

Review 5.  New Therapeutic Perceptions in a Patient with Complicated Herpes Simplex Virus 1 Keratitis: A Case Report and Review of the Literature.

Authors:  Dimitrios Kalogeropoulos; Aliki Geka; Konstantinos Malamos; Maria Kanari; Chris Kalogeropoulos
Journal:  Am J Case Rep       Date:  2017-12-27
  5 in total

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