Hatem Soliman1, Samuel V Agresta. 1. Sarcoma Program, H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL 33612, USA. hatem.soliman@moffitt.org
Abstract
BACKGROUND: Overall, the survival rate for cancer patients has continued to improve over the past several decades. However, those aged 15 to 29 years have not experienced the same improvements in survival. This review explores some of the challenges faced by adolescent and young adult (AYA) cancer patients and their survivorship needs. METHODS: Using the OVID Medline database from 1966 to present, a variety of search terms including "adolescent," "young adult," and "cancer survivorship" were entered. Articles related to those obtained by the search were also collected. Additional data were obtained from the SEER database AYA monograph, the Childhood Cancer Survivorship Study, the Report of the Adolescent and Young Adult Oncology Progress Review Group, and the Long-Term Follow-Up Recommendations of the Children's Oncology Group. RESULTS: Cancer patients in this age-group are at increased risk for second malignancies, cardiotoxicity, and reproductive difficulties. Few data exist concerning intellectual and other psychosocial issues for this specific patient population. CONCLUSIONS: More research is needed to develop accurate data on treatment and survivorship for AYA patients. A separate cancer discipline focusing on improving outcomes in treatment and survivorship among AYA patients should be developed in major academic cancer centers.
BACKGROUND: Overall, the survival rate for cancerpatients has continued to improve over the past several decades. However, those aged 15 to 29 years have not experienced the same improvements in survival. This review explores some of the challenges faced by adolescent and young adult (AYA) cancerpatients and their survivorship needs. METHODS: Using the OVID Medline database from 1966 to present, a variety of search terms including "adolescent," "young adult," and "cancer survivorship" were entered. Articles related to those obtained by the search were also collected. Additional data were obtained from the SEER database AYA monograph, the Childhood Cancer Survivorship Study, the Report of the Adolescent and Young Adult Oncology Progress Review Group, and the Long-Term Follow-Up Recommendations of the Children's Oncology Group. RESULTS:Cancerpatients in this age-group are at increased risk for second malignancies, cardiotoxicity, and reproductive difficulties. Few data exist concerning intellectual and other psychosocial issues for this specific patient population. CONCLUSIONS: More research is needed to develop accurate data on treatment and survivorship for AYA patients. A separate cancer discipline focusing on improving outcomes in treatment and survivorship among AYA patients should be developed in major academic cancer centers.
Authors: Helen M Parsons; Linda C Harlan; Nita L Seibel; Jennifer L Stevens; Theresa H M Keegan Journal: J Clin Oncol Date: 2011-09-19 Impact factor: 44.544
Authors: Gwendolyn P Quinn; Devin Murphy; Caprice Knapp; Daniel K Stearsman; Kathy L Bradley-Klug; Kelly Sawczyn; Marla L Clayman Journal: J Adolesc Health Date: 2011-03-15 Impact factor: 5.012
Authors: Mariko L Carey; Tara Clinton-McHarg; Robert William Sanson-Fisher; Anthony Shakeshaft Journal: Support Care Cancer Date: 2011-05-01 Impact factor: 3.603
Authors: Tara Clinton-McHarg; Mariko Carey; Rob Sanson-Fisher; Anthony Shakeshaft; Kathy Rainbird Journal: Health Qual Life Outcomes Date: 2010-03-06 Impact factor: 3.186