Literature DB >> 18094366

Obesity impacts access to kidney transplantation.

Dorry L Segev1, Christopher E Simpkins, Richard E Thompson, Jayme E Locke, Daniel S Warren, Robert A Montgomery.   

Abstract

Current billing practices and mandates to report surgical outcomes are disincentives to surgical treatment of obese patients, who are at increased risk for longer hospital stays and higher complication rates. The objective of this study was to quantify the independent association between body mass index (BMI) and waiting time for kidney transplantation to identify potential provider bias against surgical treatment of the obese. A secondary data analysis was performed of a prospective cohort of 132,353 patients who were registered for kidney transplantation in the United States between 1995 and 2006. Among all patients awaiting kidney transplantation, the likelihood of receiving a transplant decreased with increasing degree of obesity, categorized by ranges of BMI (adjusted hazard ratios 0.96 for overweight, 0.93 for obese, 0.72 for severely obese, and 0.56 for morbidly obese, compared with a reference group of patients with normal BMI). Similarly, the likelihood of being bypassed when an organ became available increased in a graded manner with category of obesity (adjusted incidence rate ratio 1.02 for overweight, 1.05 for obese, 1.11 for severely obese, and 1.22 for morbidly obese). Although matching an available organ with an appropriate recipient requires clinical judgment, which could not be fully captured in this study, the observed differences are dramatic and warrant further studies to understand this effect better and to design a system that is less susceptible to unintended bias.

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Mesh:

Year:  2007        PMID: 18094366      PMCID: PMC2396750          DOI: 10.1681/ASN.2007050610

Source DB:  PubMed          Journal:  J Am Soc Nephrol        ISSN: 1046-6673            Impact factor:   10.121


  26 in total

1.  Cream-skimming, incentives for efficiency and payment system.

Authors:  Pedro Pita Barros
Journal:  J Health Econ       Date:  2003-05       Impact factor: 3.883

2.  Public reporting of surgical mortality: a survey of New York State cardiothoracic surgeons.

Authors:  J H Burack; P Impellizzeri; P Homel; J N Cunningham
Journal:  Ann Thorac Surg       Date:  1999-10       Impact factor: 4.330

Review 3.  Survival benefit of kidney and liver transplantation for obese patients on the waiting list.

Authors:  Shawn J Pelletier; Martin A Maraschio; Douglas E Schaubel; Dawn M Dykstra; Jeffrey D Punch; Robert A Wolfe; Friedrich K Port; Robert M Merion
Journal:  Clin Transpl       Date:  2003

4.  Morbid obesity is not a contraindication to kidney transplantation.

Authors:  William H Marks; Lisa S Florence; Philip H Chapman; Andrew F Precht; Diana T Perkinson
Journal:  Am J Surg       Date:  2004-05       Impact factor: 2.565

Review 5.  The risks of surgery in obese patients.

Authors:  P S Pasulka; B R Bistrian; P N Benotti; G L Blackburn
Journal:  Ann Intern Med       Date:  1986-04       Impact factor: 25.391

6.  Obesity in general elective surgery.

Authors:  Daniel Dindo; Markus K Muller; Markus Weber; Pierre-Alain Clavien
Journal:  Lancet       Date:  2003-06-14       Impact factor: 79.321

7.  Impact of renal transplantation on survival in end-stage renal disease patients with elevated body mass index.

Authors:  Christopher W Glanton; Tzu-Cheg Kao; David Cruess; Lawrence Y C Agodoa; Kevin C Abbott
Journal:  Kidney Int       Date:  2003-02       Impact factor: 10.612

8.  Increased incidence of nosocomial infections in obese surgical patients.

Authors:  P S Choban; R Heckler; J C Burge; L Flancbaum
Journal:  Am Surg       Date:  1995-11       Impact factor: 0.688

9.  Outmigration for coronary bypass surgery in an era of public dissemination of clinical outcomes.

Authors:  N A Omoigui; D P Miller; K J Brown; K Annan; D Cosgrove; B Lytle; F Loop; E J Topol
Journal:  Circulation       Date:  1996-01-01       Impact factor: 29.690

10.  Nosocomial infections and obesity in surgical patients.

Authors:  Zeynep Cantürk; Nuh Zafer Cantürk; Berrin Cetinarslan; Nihat Zafer Utkan; Ilhan Tarkun
Journal:  Obes Res       Date:  2003-06
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  55 in total

1.  The Other Half of Informed Consent: Transplant Education Practices in Dialysis Centers.

Authors:  Lauren M Kucirka; Dorry L Segev
Journal:  Clin J Am Soc Nephrol       Date:  2015-08-20       Impact factor: 8.237

2.  Bariatric Surgery Is Efficacious and Improves Access to Transplantation for Morbidly Obese Renal Transplant Candidates.

Authors:  Renana Yemini; Eviatar Nesher; Idan Carmeli; Janos Winkler; Ruth Rahamimov; Eytan Mor; Andrei Keidar
Journal:  Obes Surg       Date:  2019-08       Impact factor: 4.129

3.  Laparoscopic Sleeve Gastrectomy in Kidney Transplant Candidates: a Case Series.

Authors:  Sergio Carandina; Laurent Genser; Manuela Bossi; Laura Montana; Alexandre Cortes; Marie Seman; Marc Danan; Christophe Barrat
Journal:  Obes Surg       Date:  2017-10       Impact factor: 4.129

4.  Bariatric surgery among kidney transplant candidates and recipients: analysis of the United States renal data system and literature review.

Authors:  Kian A Modanlou; Umadevi Muthyala; Huiling Xiao; Mark A Schnitzler; Paolo R Salvalaggio; Daniel C Brennan; Kevin C Abbott; Ralph J Graff; Krista L Lentine
Journal:  Transplantation       Date:  2009-04-27       Impact factor: 4.939

5.  Obesity and cardiac risk after kidney transplantation: experience at one center and comprehensive literature review.

Authors:  Krista L Lentine; Lisa A Rocca-Rey; Giuliana Bacchi; Nadia Wasi; Leslie Schmitz; Paolo R Salvalaggio; Kevin C Abbott; Mark A Schnitzler; Luca Neri; Daniel C Brennan
Journal:  Transplantation       Date:  2008-07-27       Impact factor: 4.939

Review 6.  Paediatric obesity and renal transplantation: current challenges and solutions.

Authors:  John D Terrace; Gabriel C Oniscu
Journal:  Pediatr Nephrol       Date:  2015-05-28       Impact factor: 3.714

7.  Achieving Equity through Reducing Variability in Accepting Deceased Donor Kidney Offers.

Authors:  Sumit Mohan; Mariana C Chiles
Journal:  Clin J Am Soc Nephrol       Date:  2017-07-27       Impact factor: 8.237

8.  Bariatric Surgery as a Bridge to Renal Transplantation in Patients with End-Stage Renal Disease.

Authors:  Shadi Al-Bahri; Tannous K Fakhry; John Paul Gonzalvo; Michel M Murr
Journal:  Obes Surg       Date:  2017-11       Impact factor: 4.129

9.  Minimally invasive robotic kidney transplantation for obese patients previously denied access to transplantation.

Authors:  J Oberholzer; P Giulianotti; K K Danielson; M Spaggiari; L Bejarano-Pineda; F Bianco; I Tzvetanov; S Ayloo; H Jeon; R Garcia-Roca; J Thielke; I Tang; S Akkina; B Becker; K Kinzer; A Patel; E Benedetti
Journal:  Am J Transplant       Date:  2013-03       Impact factor: 8.086

Review 10.  Metabolic Disorders with Kidney Transplant.

Authors:  Elizabeth Cohen; Maria Korah; Glenda Callender; Renata Belfort de Aguiar; Danielle Haakinson
Journal:  Clin J Am Soc Nephrol       Date:  2020-04-13       Impact factor: 8.237

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