| Literature DB >> 18094079 |
Jaime Murphy1, Ross Summer, Alan Fine.
Abstract
Very little is known regarding the function, origin, and turnover of airway smooth muscle (ASM). In this article, we discuss the embryological development of ASM, and provide information regarding candidate mesenchymal ASM progenitor cell populations specifically in relation to airway remodeling. This review also highlights the current limitations in studying ASM biology, and underscores the need for novel molecular tools and markers that will refine our understanding of this cell type in lung homeostasis and disease.Entities:
Mesh:
Year: 2008 PMID: 18094079 PMCID: PMC2645296 DOI: 10.1513/pats.200704-052VS
Source DB: PubMed Journal: Proc Am Thorac Soc ISSN: 1546-3222