Literature DB >> 18093629

The role of estrogens and estrogen receptors in normal prostate growth and disease.

Gail S Prins1, Kenneth S Korach.   

Abstract

Estrogens have significant direct and indirect effects on prostate gland development and homeostasis and have been long suspected in playing a role in the etiology of prostatic diseases. Direct effects are mediated through prostatic estrogen receptors alpha (ERalpha) and beta (ERbeta) with expression levels changing over time and with disease progression. The present review examines the evidence for a role of estrogens and specific estrogen receptors in prostate growth, differentiation and disease states including prostatitis, benign prostatic hyperplasia (BPH) and cancer and discusses potential therapeutic strategies for growth regulation via these pathways.

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Year:  2007        PMID: 18093629      PMCID: PMC2262439          DOI: 10.1016/j.steroids.2007.10.013

Source DB:  PubMed          Journal:  Steroids        ISSN: 0039-128X            Impact factor:   2.668


  136 in total

1.  Differential expression of estrogen receptors alpha and beta in adult rat accessory sex glands and lower urinary tract.

Authors:  S Mäkelä; L Strauss; G Kuiper; E Valve; S Salmi; R Santti; J A Gustafsson
Journal:  Mol Cell Endocrinol       Date:  2000-06       Impact factor: 4.102

Review 2.  Nuclear receptor-mediated transactivation through interaction with Sp proteins.

Authors:  Stephen Safe; Kyounghyun Kim
Journal:  Prog Nucleic Acid Res Mol Biol       Date:  2004

3.  The P450 gene superfamily: recommended nomenclature.

Authors:  D W Nebert; M Adesnik; M J Coon; R W Estabrook; F J Gonzalez; F P Guengerich; I C Gunsalus; E F Johnson; B Kemper; W Levin
Journal:  DNA       Date:  1987-02

Review 4.  Long-term effects of perinatal exposure to sex steroids and diethylstilbestrol on the reproductive system of male mammals.

Authors:  Y Arai; T Mori; Y Suzuki; H A Bern
Journal:  Int Rev Cytol       Date:  1983

Review 5.  Estrogen receptors: selective ligands, partners, and distinctive pharmacology.

Authors:  B S Katzenellenbogen; M M Montano; T R Ediger; J Sun; K Ekena; G Lazennec; P G Martini; E M McInerney; R Delage-Mourroux; K Weis; J A Katzenellenbogen
Journal:  Recent Prog Horm Res       Date:  2000

6.  Cloning of the human estrogen receptor cDNA.

Authors:  P Walter; S Green; G Greene; A Krust; J M Bornert; J M Jeltsch; A Staub; E Jensen; G Scrace; M Waterfield
Journal:  Proc Natl Acad Sci U S A       Date:  1985-12       Impact factor: 11.205

7.  Effects of ageing and hormonal manipulations on the level of oestrogen receptors in the guinea-pig prostate.

Authors:  W D Tilley; D J Horsfall; M A McGee; J E Alderman; V R Marshall
Journal:  J Endocrinol       Date:  1987-01       Impact factor: 4.286

8.  Immunocytochemical localization of estrogen receptors in the normal male and female canine urinary tract and prostate.

Authors:  H Schulze; E R Barrack
Journal:  Endocrinology       Date:  1987-11       Impact factor: 4.736

9.  Hormone levels in the foetal and neonatal prostate.

Authors:  T Zondek; M D Mansfield; S L Attree; L H Zondek
Journal:  Acta Endocrinol (Copenh)       Date:  1986-07

10.  Dynamic regulation of estrogen receptor-beta expression by DNA methylation during prostate cancer development and metastasis.

Authors:  Xuegong Zhu; Irwin Leav; Yuet-Kin Leung; Mengchu Wu; Qin Liu; Ying Gao; John E McNeal; Shuk-Mei Ho
Journal:  Am J Pathol       Date:  2004-06       Impact factor: 4.307

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  86 in total

1.  Central role for PELP1 in nonandrogenic activation of the androgen receptor in prostate cancer.

Authors:  Lin Yang; Preethi Ravindranathan; Meera Ramanan; Payal Kapur; Stephen R Hammes; Jer-Tsong Hsieh; Ganesh V Raj
Journal:  Mol Endocrinol       Date:  2012-03-08

Review 2.  Mechanisms and significance of nuclear receptor auto- and cross-regulation.

Authors:  Pia Bagamasbad; Robert J Denver
Journal:  Gen Comp Endocrinol       Date:  2010-03-23       Impact factor: 2.822

3.  Antagonism of estrogen-mediated cell proliferation by raloxifene in prevention of ageing-related prostatic hyperplasia.

Authors:  Rui Yang; Yu-Xia Ma; Lin-Feng Chen; Ying Zhou; Zhan-Po Yang; Yan Zhu; Xiao-Ling Du; Jian-Dang Shi; Hong-Shun Ma; Ju Zhang
Journal:  Asian J Androl       Date:  2010-05-17       Impact factor: 3.285

4.  Progesterone as a morphological regulatory factor of the male and female gerbil prostate.

Authors:  Ricardo A Fochi; Fernanda C A Santos; Rejane M Goes; Sebastião R Taboga
Journal:  Int J Exp Pathol       Date:  2013-12       Impact factor: 1.925

Review 5.  Molecular signaling pathways that regulate prostate gland development.

Authors:  Gail S Prins; Oliver Putz
Journal:  Differentiation       Date:  2008-05-07       Impact factor: 3.880

6.  Estrogen receptor beta protects against in vivo injury in RPE cells.

Authors:  Sharon J Elliot; Paola Catanuto; Diego G Espinosa-Heidmann; Pedro Fernandez; Eleut Hernandez; Peter Saloupis; Kenneth Korach; Michael Karl; Scott W Cousins
Journal:  Exp Eye Res       Date:  2009-09-30       Impact factor: 3.467

Review 7.  Androgens and estrogens in benign prostatic hyperplasia: past, present and future.

Authors:  Tristan M Nicholson; William A Ricke
Journal:  Differentiation       Date:  2011-05-26       Impact factor: 3.880

8.  Exposure to ethinylestradiol during prenatal development and postnatal supplementation with testosterone causes morphophysiological alterations in the prostate of male and female adult gerbils.

Authors:  Ana Paula Silva Perez; Manoel Francisco Biancardi; Rejane Maira Góes; Fernanda Alcântara dos Santos; Sebastião Roberto Taboga
Journal:  Int J Exp Pathol       Date:  2011-02-12       Impact factor: 1.925

9.  Estrogen receptor alpha gene polymorphisms and risk of prostate cancer: a meta-analysis involving 18 studies.

Authors:  Zhenwei Gu; Gang Wang; Weiguo Chen
Journal:  Tumour Biol       Date:  2014-03-01

10.  Tissue-specific quantification and localization of androgen and estrogen receptors in prostate cancer.

Authors:  Priyanka D Sehgal; Tyler M Bauman; Tristan M Nicholson; Jordan E Vellky; Emily A Ricke; Weiping Tang; Wei Xu; Wei Huang; William A Ricke
Journal:  Hum Pathol       Date:  2019-05-03       Impact factor: 3.466

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