Literature DB >> 18092794

A terphenyl scaffold for pi-stacked guanidinium recognition elements.

Xing Wang1, Olga V Sarycheva, Bryan D Koivisto, Aaron H McKie, Fraser Hof.   

Abstract

A new synthetic model of arginine-carboxylate-aromatic triads-common motifs at sites of protein-protein interactions-is reported. Binding studies in mixed methanol/water solvent systems suggest that the carboxylate-binding ability of pi-stacked guanidinium ions is improved relative to a non-stacked control.

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Year:  2007        PMID： 18092794     DOI： 10.1021/ol7027042

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  2 in total

1.  Thermodynamic computational approach to capture molecular recognition in the binding of different inhibitors to the DNA gyrase B subunit from Escherichia coli.

Authors:  Liane Saíz-Urra; Miguel Ángel Cabrera Pérez; Matheus Froeyen
Journal:  J Mol Model       Date:  2013-04-30       Impact factor: 1.810

2.  Geometries of stacking interactions between phenanthroline ligands in crystal structures of square-planar metal complexes.

Authors:  Goran V Janjić; Predrag V Petrović; Dragan B Ninković; Snežana D Zarić
Journal:  J Mol Model       Date:  2010-12-16       Impact factor: 1.810
  2 in total

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