| Literature DB >> 18092097 |
Merja A Neukamm1, Antonio Pinto, Nils Metzler-Nolte.
Abstract
A solid-phase synthesized propargyl derivative of the neuropeptide leucine-enkephalin (Enk) reacts rapidly and quantitatively with Co(2)(CO)(8) to give the Co(2)(CO)(6)-alkyne labeled peptide , which is the first organometallic peptide bioconjugate to show significant toxicity against two different tumor cell lines.Entities:
Mesh：
Substances：
Year: 2007 PMID： 18092097 DOI： 10.1039/b712886j
Source DB: PubMed Journal: Chem Commun (Camb) ISSN： 1359-7345 Impact factor: 6.222