Literature DB >> 18090765

Gross and pathologic analysis of long-term silicone implants inserted into the human body for augmentation rhinoplasty: 221 revision cases.

Dong Hak Jung1, Bum Ryul Kim, Ji Yoon Choi, Young Soo Rho, Hyo Jin Park, Wade W Han.   

Abstract

BACKGROUND: In augmentation rhinoplasty, delayed morphologic changes are often observed with silicone implants, despite them being known as a safe implant material. The purpose of this study was to identify the cause and time course of delayed shape changes of silicone implants, through the long-term evaluation of inserted implants and their surrounding nasal soft tissues after their removal at revision rhinoplasty operations.
METHODS: Two hundred twenty-one silicone implants removed during revision rhinoplasty were studied. The period of insertion ranged from 1 month to 25 years, with an average of 6 years 7 months. Calcification within the silicone implants and, when available, the capsular soft-tissue attachments were examined with the naked eye and light microscopy.
RESULTS: Calcification was first observed grossly with the naked eye after 5 years 8 months of insertion. With light microscopy, calcification debris could be seen after 4 years. After implant insertion for more than 9 years, focal calcification could be seen in 50 percent of implants. When implants had been inserted for more than 15 years, a denatured type of large calcification was clearly observed. Plasma cell, macrophage, and neutrophil proliferation was noted in the soft-tissue capsule surrounding the superficial calcifications in those individuals with an early inflammatory response, and lymphocyte proliferation was noted in those with a late inflammatory response.
CONCLUSIONS: Silicone implants were noted to induce calcification when inserted for a long time, causing long-term morphologic changes. This should be taken into consideration when choosing silicone implants for augmentation rhinoplasty.

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Year:  2007        PMID: 18090765     DOI: 10.1097/01.prs.0000287323.71630.e6

Source DB:  PubMed          Journal:  Plast Reconstr Surg        ISSN: 0032-1052            Impact factor:   4.730


  9 in total

1.  The association of matrix Gla protein isomers with calcification in capsules surrounding silicone breast implants.

Authors:  Larry W Hunter; John C Lieske; Nho V Tran; Virginia M Miller
Journal:  Biomaterials       Date:  2011-08-11       Impact factor: 12.479

2.  Contracted Nose after Silicone Implantation: A New Classification System and Treatment Algorithm.

Authors:  Yong Kyu Kim; Seungho Shin; Nak Heon Kang; Joo Heon Kim
Journal:  Arch Plast Surg       Date:  2017-01-20

3.  Crushed Cartilage and Autologous Fat for Dorsal Nasal Refinement.

Authors:  Arvind U Gowda; Navid Pourtaheri; Kitae E Park; Omar Allam; Seija Maniskas; Yassmin Parsaei; Derek M Steinbacher
Journal:  Aesthetic Plast Surg       Date:  2021-04-05       Impact factor: 2.326

4.  Calcinosis cutis long after rhinoplasty with silicone.

Authors:  Yuki Honda; Hideaki Tanizaki; Atsushi Otsuka; Yoshiki Miyachi; Kenji Kabashima
Journal:  Case Rep Dermatol       Date:  2014-12-16

5.  Corrective Rhinoplasty with Combined Use of Autogenous Auricular Cartilage and Porcine Dermal Collagen in Cleft Lip Nose Deformity.

Authors:  Young-Wook Park
Journal:  Maxillofac Plast Reconstr Surg       Date:  2014-09-30

6.  Silicone Implant Sandwiched between Intact Nasal Bones with Fractured Nasal Bone Segments.

Authors:  Soo Hyun Woo; Woo Seob Kim; Han Koo Kim; Tae Hui Bae
Journal:  Arch Craniofac Surg       Date:  2017-03-25

7.  Osteopontin (OPN) is an important protein to mediate improvements in the biocompatibility of C ion-implanted silicone rubber.

Authors:  Shao-liang Wang; Xiao-hua Shi; Zhi Yang; Yi-ming Zhang; Li-ru Shen; Ze-yuan Lei; Zhi-Qing Zhang; Cong Cao; Dong-li Fan
Journal:  PLoS One       Date:  2014-06-09       Impact factor: 3.240

8.  Current update in asian rhinoplasty.

Authors:  Clyde H Ishii
Journal:  Plast Reconstr Surg Glob Open       Date:  2014-05-07

9.  Effective Use of a Silicone-induced Capsular Flap in Secondary Asian Rhinoplasty.

Authors:  Jae Yong Jeong; Sang-Ha Oh; Man Koon Suh; Chang Kyung Kim; Kenneth K Kim
Journal:  Plast Reconstr Surg Glob Open       Date:  2014-07-09
  9 in total

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