AIMS AND OBJECTIVES: To evaluate whether gender, age and their interaction affect health-related quality of life and overall health status following kidney transplantation. BACKGROUND: Some investigators have examined the main effects of gender and/or age on health-related quality of life following kidney transplantation, but the potential interaction effect of these measures on this outcome has not been reported. DESIGN: This was a cross-sectional, single-centre study, based in one US geographic area. METHODS: Self-report survey data were provided by adult kidney transplant recipients using the SF-36 Health Survey (SF-36) and a visual analogue scale of overall health. SF-36 physical and mental component summary and individual scales and overall health were measured prospectively at one time point post-transplant. All adult patients were eligible to participate and rolling enrolment was employed. Statistical effects were tested using analysis of covariance (controlling for time post-transplant). RESULTS: Subjects (n = 138) included 66 women and 72 men. There were no effects of gender, age group, or their interaction on MCS or overall health scores (all p >or= 0.12). Physical component summary scale data demonstrated: (i) a significant effect of gender (p = 0.025); (ii) a statistically marginal effect of age group (p = 0.068); and (iii) a statistically marginal gender by age group interaction effect (p = 0.066). Women reported poorer scores on the SF-36 physical functioning (p = 0.049), role physical (p = 0.014) and bodily pain scales (p = 0.028). There was an effect of age group on physical functioning (p = 0.005), with younger patients reporting higher scores. CONCLUSIONS: Women report lower scores on several physical measures and may experience a greater reduction with age in physical health-related quality of life than men. Physical functioning declines with age following kidney transplantation. RELEVANCE TO CLINICAL PRACTICE: Findings may help healthcare professionals to develop gender- and age-specific interventions to optimize health-related quality of life of kidney transplant patients.
AIMS AND OBJECTIVES: To evaluate whether gender, age and their interaction affect health-related quality of life and overall health status following kidney transplantation. BACKGROUND: Some investigators have examined the main effects of gender and/or age on health-related quality of life following kidney transplantation, but the potential interaction effect of these measures on this outcome has not been reported. DESIGN: This was a cross-sectional, single-centre study, based in one US geographic area. METHODS: Self-report survey data were provided by adult kidney transplant recipients using the SF-36 Health Survey (SF-36) and a visual analogue scale of overall health. SF-36 physical and mental component summary and individual scales and overall health were measured prospectively at one time point post-transplant. All adult patients were eligible to participate and rolling enrolment was employed. Statistical effects were tested using analysis of covariance (controlling for time post-transplant). RESULTS: Subjects (n = 138) included 66 women and 72 men. There were no effects of gender, age group, or their interaction on MCS or overall health scores (all p >or= 0.12). Physical component summary scale data demonstrated: (i) a significant effect of gender (p = 0.025); (ii) a statistically marginal effect of age group (p = 0.068); and (iii) a statistically marginal gender by age group interaction effect (p = 0.066). Women reported poorer scores on the SF-36 physical functioning (p = 0.049), role physical (p = 0.014) and bodily pain scales (p = 0.028). There was an effect of age group on physical functioning (p = 0.005), with younger patients reporting higher scores. CONCLUSIONS:Women report lower scores on several physical measures and may experience a greater reduction with age in physical health-related quality of life than men. Physical functioning declines with age following kidney transplantation. RELEVANCE TO CLINICAL PRACTICE: Findings may help healthcare professionals to develop gender- and age-specific interventions to optimize health-related quality of life of kidney transplant patients.
Authors: Rachel C Forbes; Irene D Feurer; David LaNeve; Beatrice P Concepcion; Christianna Gamble; Scott A Rega; C Wright Pinson; David Shaffer Journal: Clin Transplant Date: 2018-03-30 Impact factor: 2.863
Authors: Sarah Batawi; Nehal Tarazan; Rajaa Al-Raddadi; Eman Al Qasim; Anees Sindi; Sameera Al Johni; Fahad M Al-Hameed; Yaseen M Arabi; Timothy M Uyeki; Basem M Alraddadi Journal: Health Qual Life Outcomes Date: 2019-06-11 Impact factor: 3.186
Authors: Nanna von der Lippe; Bård Waldum; Tone-Brit Hortemo Østhus; Anna Varberg Reisæter; Ingrid Os Journal: BMC Womens Health Date: 2014-03-01 Impact factor: 2.809