Daven N Doshi1, Kaija K Hanneman, Kevin D Cooper. 1. Department of Dermatology, Case Western Reserve University, Bolwell Health Center, 11100 Euclid Ave, Ste 3100, Cleveland, OH 44106, USA. doshid@gwu.edu
Abstract
BACKGROUND: A twin pair can provide a rare opportunity to control for genetic susceptibility and exposure variables, which often serve as major confounders in population-based studies on the relationship between smoking and skin aging. OBSERVATIONS: We describe a unique twin pair who spent not only their first 2 decades of life together but also in their later decades had the same type of job at the same latitude, resulting in well-matched levels of significant sun exposure. However, the twins differed markedly in regard to smoking history; the twin with an approximately 52.5-pack-year smoking history showed more severe skin aging than did the nonsmoking twin. CONCLUSION: The difference in skin aging illustrated by this twin pair may serve as a motivator for smoking cessation.
BACKGROUND: A twin pair can provide a rare opportunity to control for genetic susceptibility and exposure variables, which often serve as major confounders in population-based studies on the relationship between smoking and skin aging. OBSERVATIONS: We describe a unique twin pair who spent not only their first 2 decades of life together but also in their later decades had the same type of job at the same latitude, resulting in well-matched levels of significant sun exposure. However, the twins differed markedly in regard to smoking history; the twin with an approximately 52.5-pack-year smoking history showed more severe skin aging than did the nonsmoking twin. CONCLUSION: The difference in skin aging illustrated by this twin pair may serve as a motivator for smoking cessation.
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Authors: Peter J Nicksic; Alison M Karczewski; Qianqian Zhao; Nicholas A Garcia; Brett F Michelotti; Ashish Y Mahajan; Samuel O Poore Journal: Aesthet Surg J Open Forum Date: 2021-05-06