Literature DB >> 18086525

Synthesis and antibiotic activity of a small molecules library of 1,2,3-triazole derivatives.

Marie Aufort1, Jean Herscovici, Pascale Bouhours, Nicole Moreau, Christian Girard.   

Abstract

A small library of simple 1,4-disubstituted 1,2,3-triazoles was prepared using a known one-pot procedure starting from organic halides and terminal alkynes. The compounds were then tested for their antibacterial activity against normal and resistant species of Staphylococcus aureus.

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Year:  2007        PMID： 18086525     DOI： 10.1016/j.bmcl.2007.11.111

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN： 0960-894X            Impact factor:   2.823


  4 in total

1.  Synthesis and structure characterization of new 1,2,4-oxadiazolo[4,5-d]-1,5-benzothiazepines derivatives containing 2-phenyl-1,2,3-triazole through 1,3-dipolar cycloaddition reaction.

Authors:  De-Bao Yang; Fang-Ming Liu; Feng Xu; Chun Yang; Jia-Wei Ye; Song-Wei Shen; Ying-Lei Zhou; Wei Li
Journal:  Mol Divers       Date:  2008-07-15       Impact factor: 2.943

2.  Design and synthesis of 4,5-diphenyl-imidazol-1,2,3-triazole hybrids as new anti-diabetic agents: in vitro α-glucosidase inhibition, kinetic and docking studies.

Authors:  Mohammad Sadegh Asgari; Maryam Mohammadi-Khanaposhtani; Zeinab Sharafi; Mohammad Ali Faramarzi; Hossein Rastegar; Ensieh Nasli Esfahani; Fatemeh Bandarian; Parviz Ranjbar Rashidi; Rahmatollah Rahimi; Mahmood Biglar; Mohammad Mahdavi; Bagher Larijani
Journal:  Mol Divers       Date:  2020-03-18       Impact factor: 2.943

3.  Design and synthesis of new chacones substituted with azide/triazole groups and analysis of their cytotoxicity towards HeLa cells.

Authors:  Graziele D da Silva; Marina G da Silva; Estrela M P V E Souza; Andersson Barison; Sarah C Simões; Fernando P Varotti; Leandro A Barbosa; Gustavo H R Viana; José A F P Villar
Journal:  Molecules       Date:  2012-08-29       Impact factor: 4.411

4.  The synthesis, antiviral, cytostatic and cytotoxic evaluation of a new series of acyclonucleotide analogues with a 1,2,3-triazole linker.

Authors:  Iwona E Głowacka; Jan Balzarini; Andrzej E Wróblewski
Journal:  Eur J Med Chem       Date:  2013-10-30       Impact factor: 6.514
  4 in total

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