Literature DB >> 18085786

A mechanistic design principle for protein tyrosine kinase sensors: application to a validated cancer target.

Aya Wakata1, Sean M Cahill, Michael Blumenstein, Rosalind H Gunby, Steffen Jockusch, Angel A Marti, Barbara Cimbro, Carlo Gambacorti-Passerini, Arianna Donella-Deana, Lorenzo A Pinna, Nicholas J Turro, David S Lawrence.   

Abstract

A new mechanistic principle for reporting the phosphorylation of tyrosine is described, which should prove applicable to even the most fastidious of protein tyrosine kinases, as demonstrated by the acquisition of a fluorescent sensor for the extraordinarily demanding anaplastic lymphoma kinase.

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Year:  2007        PMID： 18085786      PMCID： PMC3057043          DOI： 10.1021/ol702675b

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  12 in total

1.  A conformational flexibility scale for amino acids in peptides.

Authors:  Fang Huang; Werner M Nau
Journal:  Angew Chem Int Ed Engl       Date:  2003-05-25       Impact factor: 15.336

Review 2.  Seeing is believing: peptide-based fluorescent sensors of protein tyrosine kinase activity.

Authors:  David S Lawrence; Qunzhao Wang
Journal:  Chembiochem       Date:  2007-03-05       Impact factor: 3.164

3.  Acridones and quinacridones: novel fluorophores for fluorescence lifetime studies.

Authors:  J Anthony Smith; Richard M West; Malcolm Allen
Journal:  J Fluoresc       Date:  2004-03       Impact factor: 2.217

4.  Self-reporting fluorescent substrates of protein tyrosine kinases.

Authors:  Qunzhao Wang; Sean M Cahill; Michael Blumenstein; David S Lawrence
Journal:  J Am Chem Soc       Date:  2006-02-15       Impact factor: 15.419

Review 5.  Druggable signaling proteins.

Authors:  Mouldy Sioud; Marianne Leirdal
Journal:  Methods Mol Biol       Date:  2007

Review 6.  How do protein kinases recognize their substrates?

Authors:  L A Pinna; M Ruzzene
Journal:  Biochim Biophys Acta       Date:  1996-12-12

7.  Unique substrate specificity of anaplastic lymphoma kinase (ALK): development of phosphoacceptor peptides for the assay of ALK activity.

Authors:  Arianna Donella-Deana; Oriano Marin; Luca Cesaro; Rosalind H Gunby; Anna Ferrarese; Addolorata M L Coluccia; Carmen J Tartari; Luca Mologni; Leonardo Scapozza; Carlo Gambacorti-Passerini; Lorenzo A Pinna
Journal:  Biochemistry       Date:  2005-06-14       Impact factor: 3.162

8.  Random-coil chemical shifts of phosphorylated amino acids.

Authors:  E A Bienkiewicz; K J Lumb
Journal:  J Biomol NMR       Date:  1999-11       Impact factor: 2.835

Review 9.  Anaplastic Large Cell Lymphoma.

Authors:  L Jeffrey Medeiros; Kojo S J Elenitoba-Johnson
Journal:  Am J Clin Pathol       Date:  2007-05       Impact factor: 2.493

Review 10.  Biosensors of protein kinase action: from in vitro assays to living cells.

Authors:  Chien-An Chen; Ren-Hwa Yeh; Xiongwei Yan; David S Lawrence
Journal:  Biochim Biophys Acta       Date:  2004-03-11
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  4 in total

1.  Multicolor monitoring of dysregulated protein kinases in chronic myelogenous leukemia.

Authors:  Qunzhao Wang; Eric I Zimmerman; Alexei Toutchkine; Timothy D Martin; Lee M Graves; David S Lawrence
Journal:  ACS Chem Biol       Date:  2010-09-17       Impact factor: 5.100

2.  A broad spectrum dark quencher: construction of multiple colour protease and photolytic sensors.

Authors:  Finith E Jernigan; David S Lawrence
Journal:  Chem Commun (Camb)       Date:  2013-08-04       Impact factor: 6.222

Review 3.  Interrogating Protein Phosphatases with Chemical Activity Probes.

Authors:  Garrett R Casey; Cliff I Stains
Journal:  Chemistry       Date:  2018-03-08       Impact factor: 5.236

Review 4.  Selective Sensing of Tyrosine Phosphorylation in Peptides Using Terbium(III) Complexes.

Authors:  Jun Sumaoka; Hiroki Akiba; Makoto Komiyama
Journal:  Int J Anal Chem       Date:  2016-06-08       Impact factor: 1.885
  4 in total

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