Literature DB >> 18085397

Adult height of three renal transplant patients after growth hormone therapy.

Osamu Motoyama1, Akira Hasegawa2, Takeshi Kawamura2, Atushi Aikawa2, Kikuo Iitaka3.   

Abstract

Three girls with normal growth hormone secretion had received renal transplantation when aged 2 to 6 years. They had had severely retarded growth (SD for height score was -7.4 to -3.7) at the time of transplantation. After renal transplantation, steroid was withdrawn and they were treated with recombinant human growth hormone; they subsequently reached adult heights of 145 to 156 cm. The SD for adult height score was -2.6 to -0.3. The adult height in two patients was over their target height, calculated using the mean of the parents' height. This report shows the efficacy of steroid withdrawal and recombinant human growth hormone therapy in achieving adult height in these three girls after renal transplantation.

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Year:  2007        PMID: 18085397     DOI: 10.1007/s10157-007-0491-6

Source DB:  PubMed          Journal:  Clin Exp Nephrol        ISSN: 1342-1751            Impact factor:   2.801


  8 in total

1.  Predictors of final adult height after renal transplantation during childhood: a single-center study.

Authors:  J Rodríguez-Soriano; A Vallo; M J Quintela; S Málaga; C Loris
Journal:  Nephron       Date:  2000-11       Impact factor: 2.847

2.  Long-term use of recombinant human growth hormone in pediatric allograft recipients: a report of the NAPRTCS Transplant Registry.

Authors:  Richard N Fine; Donald Stablein
Journal:  Pediatr Nephrol       Date:  2005-01-29       Impact factor: 3.714

3.  Growth over 10 years following a 1-year trial of growth hormone therapy.

Authors:  L Rees; G Ward; S P Rigden
Journal:  Pediatr Nephrol       Date:  2000-04       Impact factor: 3.714

4.  Kidney transplanted children come of age.

Authors:  G Offner; K Latta; P F Hoyer; H J Baum; J H Ehrich; R Pichlmayr; J Brodehl
Journal:  Kidney Int       Date:  1999-04       Impact factor: 10.612

5.  Impact of growth hormone treatment on a Belgian population of short children with renal allografts.

Authors:  F Janssen; R Van Damme-Lombaerts; M Van Dyck; M Hall; T Schurmans; J Herman; L Hooghe; B Van Damme
Journal:  Pediatr Transplant       Date:  1997-11

6.  A prospective trial of steroid withdrawal after renal transplantation treated with cyclosporine and mizoribine in children: results obtained between 1990 and 2003.

Authors:  Osamu Motoyama; Akira Hasegawa; Takehiro Ohara; Mari Satoh; Seiichirou Shishido; Masataka Honda; Kazuo Tsuzuki; Tsuneo Kinukawa; Motoshi Hattori; Katsumi Ito; Osamu Ogawa; Toshio Yanagihara; Kazuhide Saito; Kota Takahashi; Shinichi Ohshima
Journal:  Pediatr Transplant       Date:  2005-04

7.  The use of plasma creatinine concentration for estimating glomerular filtration rate in infants, children, and adolescents.

Authors:  G J Schwartz; L P Brion; A Spitzer
Journal:  Pediatr Clin North Am       Date:  1987-06       Impact factor: 3.278

8.  [The effects of recombinant human growth hormone (r-hGH, SM-9500, genotropin) on growth disturbance in children after renal transplantation. Japanese Multi-Center Study (Genotropin) Group on Children with Renal Disease].

Authors:  K Ito; H Kawaguchi; K Shizume; I Hibi
Journal:  Nihon Jinzo Gakkai Shi       Date:  1995-03
  8 in total
  1 in total

Review 1.  Mechanism and Treatment Strategy of Osteoporosis after Transplantation.

Authors:  Lei Song; Xu-Biao Xie; Long-Kai Peng; Shao-Jie Yu; Ya-Ting Peng
Journal:  Int J Endocrinol       Date:  2015-07-27       Impact factor: 3.257

  1 in total

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