Literature DB >> 18084959

Src kinase and pancreatic cancer.

A Hilbig1.   

Abstract

The c-Src non-receptor tyrosine kinase is overexpressed in a large number of human malignancies. It is linked to tumour development and progression to distant metastases by promoting cell proliferation, invasion, and motility. Recently, promising anticancer therapeutics targeting c-Src have been developed that are under clinical investigation.

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Year:  2008        PMID： 18084959     DOI： 10.1007/978-3-540-71279-4_19

Source DB:  PubMed          Journal:  Recent Results Cancer Res        ISSN： 0080-0015


  8 in total

1.  TKS5-positive invadopodia-like structures in human tumor surgical specimens.

Authors:  Yu-Chuan Chen; Matthew Baik; Joshua T Byers; Kathryn T Chen; Samuel W French; Begoña Díaz
Journal:  Exp Mol Pathol       Date:  2018-11-12       Impact factor: 3.362

2.  Mechanisms underlying the cytotoxicity of a novel quinazolinedione-based redox modulator, QD232, in pancreatic cancer cells.

Authors:  Divya Pathania; Yuting Kuang; Mario Sechi; Nouri Neamati
Journal:  Br J Pharmacol       Date:  2015-01       Impact factor: 8.739

3.  Nicotine, IFN-γ and retinoic acid mediated induction of MUC4 in pancreatic cancer requires E2F1 and STAT-1 transcription factors and utilize different signaling cascades.

Authors:  Sateesh Kunigal; Moorthy P Ponnusamy; Navneet Momi; Surinder K Batra; Srikumar P Chellappan
Journal:  Mol Cancer       Date:  2012-04-26       Impact factor: 27.401

4.  Role of c-Src activity in the regulation of gastric cancer cell migration.

Authors:  Yun Yang; Zhi-Gang Bai; Jie Yin; Guo-Cong Wu; Zhong-Tao Zhang
Journal:  Oncol Rep       Date:  2014-05-15       Impact factor: 3.906

5.  C-Src confers resistance to mitotic stress through inhibition DMAP1/Bub3 complex formation in pancreatic cancer.

Authors:  Jingjie Li; Bin Hu; Ting Wang; Wenhua Huang; Chunmin Ma; Qin Zhao; Lingang Zhuo; Tao Zhang; Yuhui Jiang
Journal:  Mol Cancer       Date:  2018-12-15       Impact factor: 27.401

6.  Annexin 2 has a dual role as regulator and effector of v-Src in cell transformation.

Authors:  Matthew J Hayes; Stephen E Moss
Journal:  J Biol Chem       Date:  2009-02-04       Impact factor: 5.157

7.  Fyn/heterogeneous nuclear ribonucleoprotein E1 signaling regulates pancreatic cancer metastasis by affecting the alternative splicing of integrin β1.

Authors:  Peng Jiang; Zhonghu Li; Feng Tian; Xiaowu Li; Jin Yang
Journal:  Int J Oncol       Date:  2017-05-24       Impact factor: 5.650

8.  The Pyrazolo[3,4-d]Pyrimidine Derivative Si306 Encapsulated into Anti-GD2-Immunoliposomes as Therapeutic Treatment of Neuroblastoma.

Authors:  Enrico Rango; Fabio Pastorino; Chiara Brignole; Arianna Mancini; Federica Poggialini; Salvatore Di Maria; Claudio Zamperini; Giulia Iovenitti; Anna Lucia Fallacara; Samantha Sabetta; Letizia Clementi; Massimo Valoti; Silvia Schenone; Adriano Angelucci; Mirco Ponzoni; Elena Dreassi; Maurizio Botta
Journal:  Biomedicines       Date:  2022-03-12
  8 in total

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