Literature DB >> 18084920

Natural products from plant cell cultures.

Elizabeth McCoy1, Sarah E O'Connor.   

Abstract

Plants produce complex small molecules - natural products - that exhibit anticancer, antimalarial and antimicrobial activity. These molecules play a key role in human medicine. However, plants typically produce these compounds in low quantities, and harvesting plant natural products is frequently expensive, time-consuming and environmentally damaging. Plant cell culture provides a renewable, easily scalable source of plant material. In this chapter we discuss the successes and pitfalls associated with natural product production in plant cell cultures.

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Year:  2008        PMID: 18084920

Source DB:  PubMed          Journal:  Prog Drug Res        ISSN: 0071-786X


  5 in total

Review 1.  Natural products as chemical probes.

Authors:  Erin E Carlson
Journal:  ACS Chem Biol       Date:  2010-07-16       Impact factor: 5.100

2.  Opportunities in metabolic engineering to facilitate scalable alkaloid production.

Authors:  Effendi Leonard; Weerawat Runguphan; Sarah O'Connor; Kristala Jones Prather
Journal:  Nat Chem Biol       Date:  2009-05       Impact factor: 15.040

Review 3.  Natural products: a continuing source of novel drug leads.

Authors:  Gordon M Cragg; David J Newman
Journal:  Biochim Biophys Acta       Date:  2013-02-18

4.  Optimization of yeast-based production of medicinal protoberberine alkaloids.

Authors:  Stephanie Galanie; Christina D Smolke
Journal:  Microb Cell Fact       Date:  2015-09-16       Impact factor: 5.328

5.  Development of Hairy Root Cultures for Biomass and Triterpenoid Production in Centella asiatica.

Authors:  Seungeun Baek; Jong-Eun Han; Thanh-Tam Ho; So-Young Park
Journal:  Plants (Basel)       Date:  2022-01-06
  5 in total

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