| Literature DB >> 18084892 |
Thomas J Jönsson1, W Todd Lowther.
Abstract
Sulfiredoxin and sestrin are cysteine sulfinic acid reductases that selectively reduce or repair the hyperoxidized forms of typical 2-Cys peroxiredoxins within eukaryotes. As such these enzymes play key roles in the modulation of peroxide-mediated cell signaling and cellular defense mechanisms. The unique structure of sulfiredoxin facilitates access to the peroxiredoxin active site and novel sulfur chemistry.Entities:
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Year: 2007 PMID： 18084892 PMCID： PMC2391273 DOI： 10.1007/978-1-4020-6051-9_6
Source DB: PubMed Journal: Subcell Biochem ISSN： 0306-0225