Literature DB >> 18084098

Production, purification and preliminary X-ray crystallographic studies of adeno-associated virus serotype 7.

Odayme Quesada1, Brittney Gurda, Lakshmanan Govindasamy, Robert McKenna, Erik Kohlbrenner, George Aslanidi, Sergei Zolotukhin, Nicholas Muzyczka, Mavis Agbandje-McKenna.   

Abstract

Crystals of baculovirus-expressed adeno-associated virus serotype 7 capsids diffract X-rays to approximately 3.0 A resolution. The crystals belong to the rhombohedral space group R3, with unit-cell parameters a = 252.4, c = 591.2 A in the hexagonal setting. The diffraction data were processed and reduced to an overall completeness of 79.0% and an R(merge) of 12.0%. There are three viral capsids in the unit cell. The icosahedral threefold axis is coincident with the crystallographic threefold axis, resulting in one third of a capsid (20 monomers) per crystallographic asymmetric unit. The orientation of the viral capsid has been determined by rotation-function searches and is positioned at (0, 0, 0) by packing considerations.

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Year:  2007        PMID： 18084098      PMCID： PMC2344100          DOI： 10.1107/S1744309107060289

Source DB:  PubMed          Journal:  Acta Crystallogr Sect F Struct Biol Cryst Commun        ISSN： 1744-3091


  22 in total

1.  Successful production of pseudotyped rAAV vectors using a modified baculovirus expression system.

Authors:  Erik Kohlbrenner; George Aslanidi; Kevin Nash; Stanislav Shklyaev; Martha Campbell-Thompson; Barry J Byrne; Richard O Snyder; Nicholas Muzyczka; Kenneth H Warrington; Sergei Zolotukhin
Journal:  Mol Ther       Date:  2005-10-06       Impact factor: 11.454

2.  Production, purification and preliminary X-ray crystallographic studies of adeno-associated virus serotype 1.

Authors:  Edward B Miller; Brittney Gurda-Whitaker; Lakshmanan Govindasamy; Robert McKenna; Sergei Zolotukhin; Nicholas Muzyczka; Mavis Agbandje-McKenna
Journal:  Acta Crystallogr Sect F Struct Biol Cryst Commun       Date:  2006-11-30

3.  Structurally mapping the diverse phenotype of adeno-associated virus serotype 4.

Authors:  Lakshmanan Govindasamy; Eric Padron; Robert McKenna; Nicholas Muzyczka; Nikola Kaludov; John A Chiorini; Mavis Agbandje-McKenna
Journal:  J Virol       Date:  2006-09-13       Impact factor: 5.103

4.  Production, purification, crystallization and preliminary X-ray analysis of adeno-associated virus serotype 8.

Authors:  Michael Douglas Lane; Hyun Joo Nam; Eric Padron; Brittney Gurda-Whitaker; Eric Kohlbrenner; George Aslanidi; Barry Byrne; Robert McKenna; Nicholas Muzyczka; Sergei Zolotukhin; Mavis Agbandje-McKenna
Journal:  Acta Crystallogr Sect F Struct Biol Cryst Commun       Date:  2005-06-01

5.  Structure of adeno-associated virus serotype 8, a gene therapy vector.

Authors:  Hyun-Joo Nam; Michael Douglas Lane; Eric Padron; Brittney Gurda; Robert McKenna; Erik Kohlbrenner; George Aslanidi; Barry Byrne; Nicholas Muzyczka; Sergei Zolotukhin; Mavis Agbandje-McKenna
Journal:  J Virol       Date:  2007-08-29       Impact factor: 5.103

6.  Crystallography & NMR system: A new software suite for macromolecular structure determination.

Authors:  A T Brünger; P D Adams; G M Clore; W L DeLano; P Gros; R W Grosse-Kunstleve; J S Jiang; J Kuszewski; M Nilges; N S Pannu; R J Read; L M Rice; T Simonson; G L Warren
Journal:  Acta Crystallogr D Biol Crystallogr       Date:  1998-09-01

7.  Detecting and overcoming crystal twinning.

Authors:  T O Yeates
Journal:  Methods Enzymol       Date:  1997       Impact factor: 1.600

8.  Solvent content of protein crystals.

Authors:  B W Matthews
Journal:  J Mol Biol       Date:  1968-04-28       Impact factor: 5.469

9.  Identification of amino acid residues in the capsid proteins of adeno-associated virus type 2 that contribute to heparan sulfate proteoglycan binding.

Authors:  Shaun R Opie; Kenneth H Warrington; Mavis Agbandje-McKenna; Sergei Zolotukhin; Nicholas Muzyczka
Journal:  J Virol       Date:  2003-06       Impact factor: 5.103

10.  Production, purification, crystallization and preliminary X-ray structural studies of adeno-associated virus serotype 5.

Authors:  Michael DiMattia; Lakshmanan Govindasamy; Hazel C Levy; Brittney Gurda-Whitaker; Amy Kalina; Erik Kohlbrenner; John A Chiorini; Robert McKenna; Nicholas Muzyczka; Sergei Zolotukhin; Mavis Agbandje-McKenna
Journal:  Acta Crystallogr Sect F Struct Biol Cryst Commun       Date:  2005-09-30
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  12 in total

Review 1.  Adeno-associated Virus as a Mammalian DNA Vector.

Authors:  Max Salganik; Matthew L Hirsch; Richard Jude Samulski
Journal:  Microbiol Spectr       Date:  2015-08

2.  Twinned crystals of adeno-associated virus serotype 3b prove suitable for structural studies.

Authors:  Thomas F Lerch; Qing Xie; Heather M Ongley; Joan Hare; Michael S Chapman
Journal:  Acta Crystallogr Sect F Struct Biol Cryst Commun       Date:  2009-01-31

3.  AAV9: a potential blood-brain barrier buster.

Authors:  Fredric P Manfredsson; Aaron C Rising; Ronald J Mandel
Journal:  Mol Ther       Date:  2009-03       Impact factor: 11.454

4.  The structure of adeno-associated virus serotype 3B (AAV-3B): insights into receptor binding and immune evasion.

Authors:  Thomas F Lerch; Qing Xie; Michael S Chapman
Journal:  Virology       Date:  2010-05-04       Impact factor: 3.616

5.  Structural characterization of the dual glycan binding adeno-associated virus serotype 6.

Authors:  Robert Ng; Lakshmanan Govindasamy; Brittney L Gurda; Robert McKenna; Olga G Kozyreva; R Jude Samulski; Kristin N Parent; Timothy S Baker; Mavis Agbandje-McKenna
Journal:  J Virol       Date:  2010-09-22       Impact factor: 5.103

6.  Reengineered AAV vectors: old dog, new tricks.

Authors:  Aravind Asokan
Journal:  Discov Med       Date:  2010-05       Impact factor: 2.970

7.  Structure and dynamics of adeno-associated virus serotype 1 VP1-unique N-terminal domain and its role in capsid trafficking.

Authors:  Balasubramanian Venkatakrishnan; Joseph Yarbrough; John Domsic; Antonette Bennett; Brian Bothner; Olga G Kozyreva; R Jude Samulski; Nicholas Muzyczka; Robert McKenna; Mavis Agbandje-McKenna
Journal:  J Virol       Date:  2013-02-20       Impact factor: 5.103

8.  Production, purification and preliminary X-ray crystallographic studies of adeno-associated virus serotype 9.

Authors:  Matthew Mitchell; Hyun-Joo Nam; Adam Carter; Angela McCall; Chelsea Rence; Antonette Bennett; Brittney Gurda; Robert McKenna; Mark Porter; Yoshihisa Sakai; Barry J Byrne; Nicholas Muzyczka; George Aslanidi; Sergei Zolotukhin; Mavis Agbandje-McKenna
Journal:  Acta Crystallogr Sect F Struct Biol Cryst Commun       Date:  2009-06-27

Review 9.  Perspective on Adeno-Associated Virus Capsid Modification for Duchenne Muscular Dystrophy Gene Therapy.

Authors:  Michael E Nance; Dongsheng Duan
Journal:  Hum Gene Ther       Date:  2015-10-15       Impact factor: 5.695

10.  Heparin binding induces conformational changes in Adeno-associated virus serotype 2.

Authors:  Hazel C Levy; Valorie D Bowman; Lakshmanan Govindasamy; Robert McKenna; Kevin Nash; Kenneth Warrington; Weijun Chen; Nicholas Muzyczka; Xiaodong Yan; Timothy S Baker; Mavis Agbandje-McKenna
Journal:  J Struct Biol       Date:  2008-12-13       Impact factor: 2.867
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