Literature DB >> 18083325

Residual brain infection in murine relapsing fever borreliosis can be successfully treated with ceftriaxone.

Christer Larsson1, Jenny Lundqvist, Sven Bergström.   

Abstract

Like several other spirochetes, relapsing fever Borrelia can cause persistent infection of the central nervous system (CNS). By treating mice harboring residual Borrelia duttonii brain infection with the bacteriocidal, cell wall inhibiting antibiotic ceftriaxone, bacteria were cleared from the brain. This shows that the residual infection is not latent but actively growing.

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Year:  2007        PMID: 18083325     DOI: 10.1016/j.micpath.2007.11.002

Source DB:  PubMed          Journal:  Microb Pathog        ISSN: 0882-4010            Impact factor:   3.738


  4 in total

1.  Concomitant infection decreases the malaria burden but escalates relapsing fever borreliosis.

Authors:  Jenny Lundqvist; Christer Larsson; Maria Nelson; Marie Andersson; Sven Bergström; Cathrine Persson
Journal:  Infect Immun       Date:  2010-02-09       Impact factor: 3.441

Review 2.  Relapsing fever borreliae in Africa.

Authors:  Haitham Elbir; Didier Raoult; Michel Drancourt
Journal:  Am J Trop Med Hyg       Date:  2013-08       Impact factor: 2.345

Review 3.  Pathogenesis of Relapsing Fever.

Authors:  Job Lopez; Joppe W Hovius; Sven Bergström
Journal:  Curr Issues Mol Biol       Date:  2020-12-29       Impact factor: 2.081

4.  A novel animal model of Borrelia recurrentis louse-borne relapsing fever borreliosis using immunodeficient mice.

Authors:  Christer Larsson; Jenny Lundqvist; Nico van Rooijen; Sven Bergström
Journal:  PLoS Negl Trop Dis       Date:  2009-09-29
  4 in total

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