| Literature DB >> 18083096 |
Abstract
Calcium ions (Ca(2+)) impact nearly every aspect of cellular life. This review examines the principles of Ca(2+) signaling, from changes in protein conformations driven by Ca(2+) to the mechanisms that control Ca(2+) levels in the cytoplasm and organelles. Also discussed is the highly localized nature of Ca(2+)-mediated signal transduction and its specific roles in excitability, exocytosis, motility, apoptosis, and transcription.Entities:
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Year: 2007 PMID: 18083096 DOI: 10.1016/j.cell.2007.11.028
Source DB: PubMed Journal: Cell ISSN: 0092-8674 Impact factor: 41.582