Literature DB >> 18082065

Using epidemiological and molecular methods to investigate an outbreak of gonorrhoea associated with heterosexual contact in Newcastle, NSW, Australia.

Kerry Todd1, David Durrheim, Robert Pickles, Keith Eastwood, Tony Merritt, John Tapsall, Sanghamitra Ray, Athena Limnios.   

Abstract

BACKGROUND: We report a cluster of gonorrhoea among mainly heterosexual men that occurred in October 2005, which was first identified when routine weekly surveillance review procedures indicated a three-fold increase in reporting rates compared with historical data.
METHODS: Each case was followed up with the treating medical officer to review treatment regimes and risk exposures, and to carry out enhanced contact tracing. The phenotype and genotype of the outbreak gonococcal isolates and gonococci prevalent in the months preceding and following the cluster were determined. Links between cases reported from the local Sexual Health Clinic and those reported by general practitioners were established.
RESULTS: Laboratory data indicated that a particular gonococcal subtype (ST 225 and NR/Brpyst) was prevalent during the outbreak.
CONCLUSIONS: Gonorrhoea rates returned to pre-outbreak levels following a targeted health promotion intervention with no further cases of the outbreak subtype detected.

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Year:  2007        PMID: 18082065     DOI: 10.1071/sh07037

Source DB:  PubMed          Journal:  Sex Health        ISSN: 1448-5028            Impact factor:   2.706


  4 in total

Review 1.  Review and international recommendation of methods for typing neisseria gonorrhoeae isolates and their implications for improved knowledge of gonococcal epidemiology, treatment, and biology.

Authors:  Magnus Unemo; Jo-Anne R Dillon
Journal:  Clin Microbiol Rev       Date:  2011-07       Impact factor: 26.132

2.  First neisseria gonorrhoeae genotyping analysis in france: identification of a strain cluster with reduced susceptibility to Ceftriaxone.

Authors:  Laura Monfort; Valérie Caro; Zaelle Devaux; Anne-Sophie Delannoy; Sylvain Brisse; Patrice Sednaoui
Journal:  J Clin Microbiol       Date:  2009-09-30       Impact factor: 5.948

3.  Use of whole genome sequencing to investigate an increase in Neisseria gonorrhoeae infection among women in urban areas of Australia.

Authors:  Cameron Buckley; Brian M Forde; Ella Trembizki; Monica M Lahra; Scott A Beatson; David M Whiley
Journal:  Sci Rep       Date:  2018-01-24       Impact factor: 4.379

4.  Neisseria gonorrhoeae molecular typing for understanding sexual networks and antimicrobial resistance transmission: A systematic review.

Authors:  Katy Town; Hikaru Bolt; Sara Croxford; Michelle Cole; Simon Harris; Nigel Field; Gwenda Hughes
Journal:  J Infect       Date:  2018-04-24       Impact factor: 6.072

  4 in total

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