Literature DB >> 18081690

Translational mini-review series on complement factor H: genetics and disease associations of human complement factor H.

S Rodríguez de Córdoba1, E Goicoechea de Jorge.   

Abstract

Factor H is an abundant plasma glycoprotein that plays a critical role in the regulation of the complement system in plasma and in the protection of host cells and tissues from damage by complement activation. Several recent studies have described the association of genetic variations of the complement factor H gene (CFH) with atypical haemolytic uraemic syndrome (aHUS), age-related macular degeneration (AMD) and membranoproliferative glomerulonephritis (MPGN). This review summarizes our current knowledge of CFH genetics and examines the CFH genotype-phenotype correlations that are helping to understand the molecular basis underlying these renal and ocular pathologies.

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Year:  2008        PMID： 18081690      PMCID： PMC2276932          DOI： 10.1111/j.1365-2249.2007.03552.x

Source DB:  PubMed          Journal:  Clin Exp Immunol        ISSN： 0009-9104            Impact factor:   4.330


  99 in total

1.  Complement factor H polymorphism in age-related macular degeneration.

Authors:  Robert J Klein; Caroline Zeiss; Emily Y Chew; Jen-Yue Tsai; Richard S Sackler; Chad Haynes; Alice K Henning; John Paul SanGiovanni; Shrikant M Mane; Susan T Mayne; Michael B Bracken; Frederick L Ferris; Jurg Ott; Colin Barnstable; Josephine Hoh
Journal:  Science       Date:  2005-03-10       Impact factor: 47.728

2.  Gain-of-function mutations in complement factor B are associated with atypical hemolytic uremic syndrome.

Authors:  Elena Goicoechea de Jorge; Claire L Harris; Jorge Esparza-Gordillo; Luis Carreras; Elena Aller Arranz; Cynthia Abarrategui Garrido; Margarita López-Trascasa; Pilar Sánchez-Corral; B Paul Morgan; Santiago Rodríguez de Córdoba
Journal:  Proc Natl Acad Sci U S A       Date:  2006-12-20       Impact factor: 11.205

3.  Extended haplotypes in the complement factor H (CFH) and CFH-related (CFHR) family of genes protect against age-related macular degeneration: characterization, ethnic distribution and evolutionary implications.

Authors:  Gregory S Hageman; Lisa S Hancox; Andrew J Taiber; Karen M Gehrs; Don H Anderson; Lincoln V Johnson; Monte J Radeke; David Kavanagh; Anna Richards; John Atkinson; Seppo Meri; Julie Bergeron; Jana Zernant; Joanna Merriam; Bert Gold; Rando Allikmets; Michael Dean
Journal:  Ann Med       Date:  2006       Impact factor: 4.709

4.  Y402H polymorphism of complement factor H affects binding affinity to C-reactive protein.

Authors:  Matti Laine; Hanna Jarva; Sanna Seitsonen; Karita Haapasalo; Markus J Lehtinen; Nina Lindeman; Don H Anderson; Patrick T Johnson; Irma Järvelä; T Sakari Jokiranta; Gregory S Hageman; Ilkka Immonen; Seppo Meri
Journal:  J Immunol       Date:  2007-03-15       Impact factor: 5.422

5.  Synthesis of complement factor H by retinal pigment epithelial cells is down-regulated by oxidized photoreceptor outer segments.

Authors:  Mei Chen; John V Forrester; Heping Xu
Journal:  Exp Eye Res       Date:  2006-12-31       Impact factor: 3.467

6.  Defective complement control of factor H (Y402H) and FHL-1 in age-related macular degeneration.

Authors:  Christine Skerka; Nadine Lauer; Andreas A W A Weinberger; Claudia N Keilhauer; Jürgen Sühnel; Richard Smith; Ursula Schlötzer-Schrehardt; Lars Fritsche; Stefan Heinen; Andrea Hartmann; Bernhard H F Weber; Peter F Zipfel
Journal:  Mol Immunol       Date:  2007-03-30       Impact factor: 4.407

7.  The factor H variant associated with age-related macular degeneration (His-384) and the non-disease-associated form bind differentially to C-reactive protein, fibromodulin, DNA, and necrotic cells.

Authors:  Andreas P Sjöberg; Leendert A Trouw; Simon J Clark; Jonatan Sjölander; Dick Heinegård; Robert B Sim; Anthony J Day; Anna M Blom
Journal:  J Biol Chem       Date:  2007-02-09       Impact factor: 5.157

Review 8.  An update on the genetics of age-related macular degeneration.

Authors:  Hendrik P N Scholl; Monika Fleckenstein; Peter Charbel Issa; Claudia Keilhauer; Frank G Holz; Bernhard H F Weber
Journal:  Mol Vis       Date:  2007-02-07       Impact factor: 2.367

9.  Deletion of complement factor H-related genes CFHR1 and CFHR3 is associated with atypical hemolytic uremic syndrome.

Authors:  Peter F Zipfel; Matthew Edey; Stefan Heinen; Mihály Józsi; Heiko Richter; Joachim Misselwitz; Bernd Hoppe; Danny Routledge; Lisa Strain; Anne E Hughes; Judith A Goodship; Christoph Licht; Timothy H J Goodship; Christine Skerka
Journal:  PLoS Genet       Date:  2007-02-01       Impact factor: 5.917

10.  Spontaneous hemolytic uremic syndrome triggered by complement factor H lacking surface recognition domains.

Authors:  Matthew C Pickering; Elena Goicoechea de Jorge; Rubén Martinez-Barricarte; Sergio Recalde; Alfredo Garcia-Layana; Kirsten L Rose; Jill Moss; Mark J Walport; H Terence Cook; Santiago Rodriguez de Córdoba; Marina Botto
Journal:  J Exp Med       Date:  2007-05-21       Impact factor: 14.307
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  116 in total

Review 1.  Dynamic control of the complement system by modulated expression of regulatory proteins.

Authors:  Joshua M Thurman; Brandon Renner
Journal:  Lab Invest       Date:  2010-10-04       Impact factor: 5.662

Review 2.  Complement control protein factor H: the good, the bad, and the inadequate.

Authors:  Viviana P Ferreira; Michael K Pangburn; Claudio Cortés
Journal:  Mol Immunol       Date:  2010-08       Impact factor: 4.407

Review 3.  Complement and the Kidney: An Overview.

Authors:  Joshua M Thurman
Journal:  Adv Chronic Kidney Dis       Date:  2020-03       Impact factor: 3.620

Review 4.  Principles of separation: indications and therapeutic targets for plasma exchange.

Authors:  Mark E Williams; Rasheed A Balogun
Journal:  Clin J Am Soc Nephrol       Date:  2013-10-31       Impact factor: 8.237

Review 5.  Complement's hidden arsenal: New insights and novel functions inside the cell.

Authors:  M Kathryn Liszewski; Michelle Elvington; Hrishikesh S Kulkarni; John P Atkinson
Journal:  Mol Immunol       Date:  2017-02-10       Impact factor: 4.407

Review 6.  Review: Complement and its regulatory proteins in kidney diseases.

Authors:  Allison M Lesher; Wen-Chao Song
Journal:  Nephrology (Carlton)       Date:  2010-10       Impact factor: 2.506

7.  Lack of association between polymorphisms in C4b-binding protein and atypical haemolytic uraemic syndrome in the Spanish population.

Authors:  R Martínez-Barricarte; E Goicoechea de Jorge; T Montes; A G Layana; S Rodríguez de Córdoba
Journal:  Clin Exp Immunol       Date:  2009-01       Impact factor: 4.330

Review 8.  The Neuro-Immune-Regulators (NIREGs) Promote Tissue Resilience; a Vital Component of the Host's Defense Strategy against Neuroinflammation.

Authors:  Yosra Bedoui; Jim W Neal; Philippe Gasque
Journal:  J Neuroimmune Pharmacol       Date:  2018-06-16       Impact factor: 4.147

Review 9.  The pivotal role of the complement system in aging and age-related macular degeneration: hypothesis re-visited.

Authors:  Don H Anderson; Monte J Radeke; Natasha B Gallo; Ethan A Chapin; Patrick T Johnson; Christy R Curletti; Lisa S Hancox; Jane Hu; Jessica N Ebright; Goldis Malek; Michael A Hauser; Catherine Bowes Rickman; Dean Bok; Gregory S Hageman; Lincoln V Johnson
Journal:  Prog Retin Eye Res       Date:  2009-12-02       Impact factor: 21.198

Review 10.  Advances and challenges in the management of complement-mediated thrombotic microangiopathies.

Authors:  Jean-Claude Davin; Nicole C A J van de Kar
Journal:  Ther Adv Hematol       Date:  2015-08
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