Literature DB >> 18079975

Microwave-Enhanced Fluorous Synthesis.

Wei Zhang.   

Abstract

A new technology for high-speed solution-phase parallel synthesis has been developed by the combination of microwave heating and fluorous tagging strategies. This article highlights several applications of this technology in the synthesis of library scaffolds involving Pd-catalyzed cross-coupling and multicomponent reactions.

Entities:  

Year:  2005        PMID： 18079975      PMCID： PMC2134786     

Source DB:  PubMed          Journal:  Chim Oggi        ISSN： 0392-839X


  7 in total

Review 1.  Microwave-assisted polymer-supported combinatorial synthesis.

Authors:  K M K Swamy; Wen-Ben Yeh; Mei-Jung Lin; Chung-Ming Sun
Journal:  Curr Med Chem       Date:  2003-11       Impact factor: 4.530

Review 2.  Fluorous synthesis of heterocyclic systems.

Authors:  Wei Zhang
Journal:  Chem Rev       Date:  2004-05       Impact factor: 60.622

Review 3.  Controlled microwave heating in modern organic synthesis.

Authors:  C Oliver Kappe
Journal:  Angew Chem Int Ed Engl       Date:  2004-11-26       Impact factor: 15.336

4.  Microwave-assisted synthesis of a 3-aminoimidazo[1,2-a]-pyridine/pyrazine library by fluorous multicomponent reactions and subsequent cross-coupling reactions.

Authors:  Yimin Lu; Wei Zhang
Journal:  QSAR Comb Sci       Date:  2004

5.  Solution-phase parallel synthesis of an N-alkylated dihydropteridinone library from fluorous amino acids.

Authors:  Tadamichi Nagashima; Wei Zhang
Journal:  J Comb Chem       Date:  2004 Nov-Dec

6.  A highly efficient microwave-assisted suzuki coupling reaction of aryl perfluorooctylsulfonates with boronic acids.

Authors:  Wei Zhang; Christine Hiu-Tung Chen; Yimin Lu; Tadamichi Nagashima
Journal:  Org Lett       Date:  2004-04-29       Impact factor: 6.005

7.  Combination of microwave reactions with fluorous separations in the palladium-catalyzed synthesis of aryl sulfides.

Authors:  Wei Zhang; Yimin Lu; Christine Hiu-Tung Chen
Journal:  Mol Divers       Date:  2003       Impact factor: 2.943
  7 in total

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