Literature DB >> 18076431

Globus sensation as early presentation of hypopharyngeal cancer.

A Tsikoudas1, N Ghuman, M A Riad.   

Abstract

OBJECTIVES: To identify if patients with early hypopharyngeal carcinoma can present with only the single complaint of globus sensation.
DESIGN: Retrospective case review.
SETTING: Teaching Hospital in Scotland. PARTICIPANTS: Cohort of 23 patients with hypopharyngeal carcinoma. Retrospective review of their case notes with regards to their hospital pathway from initial referral from the General Practitioner to diagnosis. OUTCOME MEASURES: Symptoms & signs on presentation, subsequent investigations and time interval between initial presentation and diagnosis.
RESULTS: We identified two patients (9%) who presented early with globus or other soft symptoms as the only complaint and with normal clinical findings. There was a 78%'pick up' rate of abnormalities in the barium swallow examination.
CONCLUSION: We believe this can have important clinical implications in the screening & investigation of globus patients who represent a significant outpatient workload. We review the relevant literature.

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Year:  2007        PMID: 18076431     DOI: 10.1111/j.1749-4486.2007.01574.x

Source DB:  PubMed          Journal:  Clin Otolaryngol        ISSN: 1749-4478            Impact factor:   2.597


  5 in total

Review 1.  [Globus sensation : A clinical review].

Authors:  C Kiese-Himmel
Journal:  HNO       Date:  2010-06       Impact factor: 1.284

2.  The Role of the Modified Barium Swallow Study and Esophagram in Patients with Globus Sensation.

Authors:  James P Dworkin; Jayme R Dowdall; Mark Kubik; Prasad John Thottam; Adam Folbe
Journal:  Dysphagia       Date:  2015-06-26       Impact factor: 3.438

3.  The role of barium swallow pharyngoesophagography in the management of the globus pharyngeus: our ten years local experience of asian population.

Authors:  Wing Hang Luk; Adrian Xu Ning Lo; Andrea Wai San Au-Yeung; Miranda Hiu Yan Lai; Yip Hin Woo; Lily Ka Man Wong; Chilene Chi Lin Chiang
Journal:  Indian J Otolaryngol Head Neck Surg       Date:  2011-11-30

4.  Pathophysiology and treatment of patients with globus sensation--from the viewpoint of esophageal motility dysfunction.

Authors:  Noriaki Manabe; Hideaki Tsutsui; Hiroaki Kusunoki; Jiro Hata; Ken Haruma
Journal:  J Smooth Muscle Res       Date:  2014

5.  Management of globus pharyngeus.

Authors:  S Kortequee; P D Karkos; H Atkinson; N Sethi; D C Sylvester; R S Harar; S Sood; W J Issing
Journal:  Int J Otolaryngol       Date:  2013-07-11
  5 in total

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