Literature DB >> 18076322

Convection-enhanced delivery for treatment of brain tumors.

Sherise D Ferguson1, Kimberly Foster, Bakhtiar Yamini.   

Abstract

Recently, innovative therapies have been developed for the treatment of malignant gliomas. Unfortunately, adequate delivery of these therapies has been a major obstacle to clinical success. Intravenous administration is restricted by the presence of the blood-brain barrier while local delivery, such as with drug-impregnated wafers, results in limited parenchyma penetration. Convection-enhanced delivery is a promising method for the delivery of macromolecules to the CNS. Convection-enhanced delivery involves the infusion of therapeutic agents via surgically implanted catheters and uses a pressure gradient to achieve a greater volume of distribution compared with that seen with diffusion alone. This article will review the development of convection-enhanced delivery and its use in the treatment of malignant gliomas.

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Year:  2007        PMID： 18076322     DOI： 10.1586/14737140.7.12s.S79

Source DB:  PubMed          Journal:  Expert Rev Anticancer Ther        ISSN： 1473-7140            Impact factor:   4.512


  10 in total

Review 1.  Biomaterials for the central nervous system.

Authors:  Yinghui Zhong; Ravi V Bellamkonda
Journal:  J R Soc Interface       Date:  2008-09-06       Impact factor: 4.118

2.  Convection-Enhanced Delivery In Silico Study for Brain Cancer Treatment.

Authors:  Chryso Lambride; Vasileios Vavourakis; Triantafyllos Stylianopoulos
Journal:  Front Bioeng Biotechnol       Date:  2022-05-25

3.  Local DNA Repair Inhibition for Sustained Radiosensitization of High-Grade Gliomas.

Authors:  Amanda R King; Christopher D Corso; Evan M Chen; Eric Song; Paul Bongiorni; Zhe Chen; Ranjini K Sundaram; Ranjit S Bindra; W Mark Saltzman
Journal:  Mol Cancer Ther       Date:  2017-05-31       Impact factor: 6.261

Review 4.  Delivery of small-interfering RNA (siRNA) to the brain.

Authors:  Saroj P Mathupala
Journal:  Expert Opin Ther Pat       Date:  2009-02       Impact factor: 6.674

5.  Neurological grading, survival, MR imaging, and histological evaluation in the rat brainstem glioma model.

Authors:  U W Thomale; B Tyler; V Renard; B Dorfman; V P Chacko; B S Carson; E J Haberl; G I Jallo
Journal:  Childs Nerv Syst       Date:  2008-12-10       Impact factor: 1.475

6.  Transcriptional targeting of glioblastoma by diphtheria toxin-A driven by both H19 and IGF2-P4 promoters.

Authors:  Doron Amit; Imad J Matouk; Iris Lavon; Tatiana Birman; Jenifer Galula; Rasha Abu-Lail; Tamar Schneider; Tali Siegal; Abraham Hochberg; Yakov Fellig
Journal:  Int J Clin Exp Med       Date:  2012-04-06

7.  Convection-Enhanced Delivery of Polymeric Nanoparticles Encapsulating Chemotherapy in Canines with Spontaneous Supratentorial Tumors.

Authors:  Jacob S Young; Giovanna Bernal; Sean P Polster; Luis Nunez; Gustavo F Larsen; Nassir Mansour; Michael Podell; Bakhtiar Yamini
Journal:  World Neurosurg       Date:  2018-06-27       Impact factor: 2.104

8.  Gene- and viral-based therapies for brain tumors.

Authors:  Kaveh Asadi-Moghaddam; E Antonio Chiocca
Journal:  Neurotherapeutics       Date:  2009-07       Impact factor: 7.620

9.  Neuronavigation-guided focused ultrasound for transcranial blood-brain barrier opening and immunostimulation in brain tumors.

Authors:  Ko-Ting Chen; Wen-Yen Chai; Ya-Jui Lin; Chia-Jung Lin; Pin-Yuan Chen; Hong-Chieh Tsai; Chiung-Yin Huang; John S Kuo; Hao-Li Liu; Kuo-Chen Wei
Journal:  Sci Adv       Date:  2021-02-05       Impact factor: 14.136

10.  Convection-enhanced delivery and in vivo imaging of polymeric nanoparticles for the treatment of malignant glioma.

Authors:  Giovanna M Bernal; Michael J LaRiviere; Nassir Mansour; Peter Pytel; Kirk E Cahill; David J Voce; Shijun Kang; Ruben Spretz; Ulrich Welp; Sandra E Noriega; Luis Nunez; Gustavo F Larsen; Ralph R Weichselbaum; Bakhtiar Yamini
Journal:  Nanomedicine       Date:  2013-07-24       Impact factor: 5.307
  10 in total

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