Literature DB >> 18075290

Proteomic analysis of human thyroid fine needle aspiration fluid.

L Giusti1, P Iacconi, F Ciregia, G Giannaccini, F Basolo, G Donatini, P Miccoli, A Lucacchini.   

Abstract

The aim of this study was to determine the protein pattern of human thyroid fine needle aspiration fluid (FNA) using a proteomic approach. FNA proteins were separated using 2-dimensional gel electrophoresis (2DE), digested and then analyzed by peptide mass fingerprinting. For the first time, we provided an image of the protein components of the FNA, in which approximately 220 protein spots can be identified. The proteome analysis revealed a specific fingerprint of FNA with proteins appertaining to various functional systems. Our preliminary results of FNA protein pattern could be a starting point in studying the presence of potential markers implicated in thyroid diseases.

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Year:  2007        PMID： 18075290     DOI： 10.1007/BF03349229

Source DB:  PubMed          Journal:  J Endocrinol Invest        ISSN： 0391-4097            Impact factor:   4.256


  15 in total

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4.  Proteomic profiling of cold thyroid nodules.

Authors:  Kerstin Krause; Stefan Karger; Angelika Schierhorn; Sylvie Poncin; Marie-Christine Many; Dagmar Fuhrer
Journal:  Endocrinology       Date:  2006-12-28       Impact factor: 4.736

5.  Quantitative and qualitative differences in protein expression between papillary thyroid carcinoma and normal thyroid tissue.

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7.  Proteomic analysis to identify breast cancer biomarkers in nipple aspirate fluid.

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Review 8.  Human body fluid proteome analysis.

Authors:  Shen Hu; Joseph A Loo; David T Wong
Journal:  Proteomics       Date:  2006-12       Impact factor: 3.984

9.  Toward the application of proteomics to human thyroid tissue.

Authors:  Kerstin Krause; Angelika Schierhorn; Andrea Sinz; Johannes-Dieter Wissmann; Annette G Beck-Sickinger; Ralf Paschke; Dagmar Fuhrer
Journal:  Thyroid       Date:  2006-11       Impact factor: 6.568

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  5 in total

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Journal:  Head Neck Pathol       Date:  2019-05-16

2.  Proteomic approach used in the diagnosis of Riedel's thyroiditis: a case report.

Authors:  Pietro Iacconi; Laura Giusti; Ylenia Da Valle; Federica Ciregia; Gino Giannaccini; Liborio Torregrossa; Agnese Proietti; Gianluca Donatini; Salvatore Mazzeo; Fulvio Basolo; Antonio Lucacchini
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Journal:  PLoS One       Date:  2013-08-26       Impact factor: 3.240

Review 4.  Molecular Signature of Indeterminate Thyroid Lesions: Current Methods to Improve Fine Needle Aspiration Cytology (FNAC) Diagnosis.

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Journal:  Int J Mol Sci       Date:  2017-04-06       Impact factor: 5.923

5.  The evolution of biomarkers in thyroid cancer-from mass screening to a personalized biosignature.

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  5 in total

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