Literature DB >> 18073912

Combined scanning optical coherence and two-photon-excited fluorescence microscopy.

E Beaurepaire, L Moreaux, F Amblard, J Mertz.   

Abstract

We demonstrate simultaneous imaging by optical coherence microscopy (OCM) and two-photon-excited (TPE) fluorescence microscopy. A mode-locked Ti:sapphire laser is focused and scanned in three dimensions through a fixed sample, generating both backscattered light and fluorescence light, which are independently detected. Both imaging modes provide rapid en-face imaging with submicrometer resolution. High-power delivery into the sample yields an OCM sensitivity in excess of 130 dB at 100-kHz pixel rates. Simultaneous imaging of cell nuclei with OCM and TPE is demonstrated in live drosophila embryos.

Entities:  

Year:  1999        PMID： 18073912     DOI： 10.1364/ol.24.000969

Source DB:  PubMed          Journal:  Opt Lett        ISSN： 0146-9592            Impact factor:   3.776


  24 in total

1.  Correction of coherence gate curvature in high numerical aperture optical coherence imaging.

Authors:  Benedikt W Graf; Steven G Adie; Stephen A Boppart
Journal:  Opt Lett       Date:  2010-09-15       Impact factor: 3.776

2.  Multimodal optical imaging system for in vivo investigation of cerebral oxygen delivery and energy metabolism.

Authors:  Mohammad A Yaseen; Vivek J Srinivasan; Iwona Gorczynska; James G Fujimoto; David A Boas; Sava Sakadžić
Journal:  Biomed Opt Express       Date:  2015-11-20       Impact factor: 3.732

3.  Imaging subcellular scattering contrast by using combined optical coherence and multiphoton microscopy.

Authors:  Shuo Tang; Chung-Ho Sun; Tatiana B Krasieva; Zhongping Chen; Bruce J Tromberg
Journal:  Opt Lett       Date:  2007-03-01       Impact factor: 3.776

4.  High-speed processing architecture for spectral-domain optical coherence microscopy.

Authors:  Robin G Chelliyil; Tyler S Ralston; Daniel L Marks; Stephen A Boppart
Journal:  J Biomed Opt       Date:  2008 Jul-Aug       Impact factor: 3.170

5.  Dual-spectrum laser source based on fiber continuum generation for integrated optical coherence and multiphoton microscopy.

Authors:  Benedikt W Graf; Zhi Jiang; Haohua Tu; Stephen A Boppart
Journal:  J Biomed Opt       Date:  2009 May-Jun       Impact factor: 3.170

6.  Fiber-based combined optical coherence and multiphoton endomicroscopy.

Authors:  Gangjun Liu; Zhongping Chen
Journal:  J Biomed Opt       Date:  2011-03       Impact factor: 3.170

7.  Noise characterization of broadband fiber Cherenkov radiation as a visible-wavelength source for optical coherence tomography and two-photon fluorescence microscopy.

Authors:  Haohua Tu; Youbo Zhao; Yuan Liu; Yuan-Zhi Liu; Stephen Boppart
Journal:  Opt Express       Date:  2014-08-25       Impact factor: 3.894

8.  Dual-modality fiber-based OCT-TPL imaging system for simultaneous microstructural and molecular analysis of atherosclerotic plaques.

Authors:  Tianyi Wang; Austin McElroy; David Halaney; Deborah Vela; Edmund Fung; Shafat Hossain; Jennifer Phipps; Bingqing Wang; Biwei Yin; Marc D Feldman; Thomas E Milner
Journal:  Biomed Opt Express       Date:  2015-04-10       Impact factor: 3.732

9.  Tri-modal microscopy with multiphoton and optical coherence microscopy/tomography for multi-scale and multi-contrast imaging.

Authors:  Shau Poh Chong; Tom Lai; Yifeng Zhou; Shuo Tang
Journal:  Biomed Opt Express       Date:  2013-08-08       Impact factor: 3.732

10.  Imaging and analysis of three-dimensional cell culture models.

Authors:  Benedikt W Graf; Stephen A Boppart
Journal:  Methods Mol Biol       Date:  2010
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.