Literature DB >> 18072099

Foxy methoxy: a new drug of abuse.

Susan C Smolinske1, Rahul Rastogi, Stephen Schenkel.   

Abstract

INTRODUCTION: In 1999, a new synthetic tryptamine, 5-MeO-DIPT, became known as a street drug, with the street name of "Foxy" or "Foxy Methoxy". By February 2003, the DEA reported law enforcement seizures and/or reports of abuse in 12 states. We report a case along with an analysis of poison center data on this new drug of abuse. CASE REPORT: A 19-year-old male was brought to the emergency department following ingestion of a larger than his usual dose of Foxy. Upon arrival, he had hallucinations, hypertension, tachycardia, mydriasis, and catalepsy. Symptoms resolved within two hours after administration of lorazepam and he recovered uneventfully. DISCUSSION: The AAPCC TESS database contained 41 exposures to "Foxy" between April, 2002 and June, 2003; 26 had moderate or major effects, indicating this drug has significant toxic potential. Given the expanding use of this and other club drugs, the spectrum of toxicity from this new agent will continue to be elucidated.

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Year:  2005        PMID: 18072099

Source DB:  PubMed          Journal:  J Med Toxicol        ISSN: 1556-9039


  14 in total

1.  Potentiation of 5-methoxy-N,N-dimethyltryptamine-induced hyperthermia by harmaline and the involvement of activation of 5-HT1A and 5-HT2A receptors.

Authors:  Xi-Ling Jiang; Hong-Wu Shen; Ai-Ming Yu
Journal:  Neuropharmacology       Date:  2015-02       Impact factor: 5.250

2.  Trends in DMT and other tryptamine use among young adults in the United States.

Authors:  Joseph J Palamar; Austin Le
Journal:  Am J Addict       Date:  2018-10

3.  Alterations in body temperature, corticosterone, and behavior following the administration of 5-methoxy-diisopropyltryptamine ('foxy') to adult rats: a new drug of abuse.

Authors:  Michael T Williams; Nicole R Herring; Tori L Schaefer; Matthew R Skelton; Nicholas G Campbell; Jack W Lipton; Anne E McCrea; Charles V Vorhees
Journal:  Neuropsychopharmacology       Date:  2006-10-18       Impact factor: 7.853

4.  Modification of 5-methoxy-N,N-dimethyltryptamine-induced hyperactivity by monoamine oxidase A inhibitor harmaline in mice and the underlying serotonergic mechanisms.

Authors:  Xi-Ling Jiang; Hong-Wu Shen; Ai-Ming Yu
Journal:  Pharmacol Rep       Date:  2016-02-05       Impact factor: 3.024

5.  Ayahuasca Exposure: Descriptive Analysis of Calls to US Poison Control Centers from 2005 to 2015.

Authors:  C William Heise; Daniel E Brooks
Journal:  J Med Toxicol       Date:  2016-11-28

6.  Behavioral, neurochemical and pharmaco-EEG profiles of the psychedelic drug 4-bromo-2,5-dimethoxyphenethylamine (2C-B) in rats.

Authors:  Tomáš Páleníček; Michaela Fujáková; Martin Brunovský; Jiří Horáček; Ingmar Gorman; Marie Balíková; Lukáš Rambousek; Kamila Syslová; Petr Kačer; Petr Zach; Věra Bubeníková-Valešová; Filip Tylš; Anna Kubešová; Jana Puskarčíková; Cyril Höschl
Journal:  Psychopharmacology (Berl)       Date:  2012-07-29       Impact factor: 4.530

7.  Comparison of the developmental effects of 5-methoxy-N,N-diisopropyltryptamine (Foxy) to (+/-)-3,4-methylenedioxymethamphetamine (ecstasy) in rats.

Authors:  Matthew R Skelton; Tori L Schaefer; Nicole R Herring; Curtis E Grace; Charles V Vorhees; Michael T Williams
Journal:  Psychopharmacology (Berl)       Date:  2009-02-06       Impact factor: 4.530

8.  Dual actions of 5-MeO-DIPT at the serotonin transporter and serotonin 5-HT1A receptor in the mouse striatum and prefrontal cortex.

Authors:  Yoko Hagino; Frank Scott Hall; George R Uhl; Ichiro Sora; Kazutaka Ikeda
Journal:  Neuropsychopharmacol Rep       Date:  2021-02-06

Review 9.  Recreational use, analysis and toxicity of tryptamines.

Authors:  Roberta Tittarelli; Giulio Mannocchi; Flaminia Pantano; Francesco Saverio Romolo
Journal:  Curr Neuropharmacol       Date:  2015-01       Impact factor: 7.363

10.  Prolonged delusional state triggered by repeated ingestion of aromatic liquid in a past 5-methoxy-N, N-diisopropyltryptamine abuser.

Authors:  Yasuko Fuse-Nagase; Toru Nishikawa
Journal:  Addict Sci Clin Pract       Date:  2013-04-11
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