Quantification of control of microbial metabolism by substrates and enzymes.

The control of substrates or enzymes on metabolic processes can be expressed in quantitative terms. Most of the experimental material found in the literature, however, has been obtained under non-standardized conditions, precluding definite conclusions concerning the magnitude of control. A number of representative examples is discussed and it is concluded that a quantitative analysis of the factors that control metabolism is essential for understanding the microbial behaviour.