Literature DB >> 18071732

Visual outcome after vitreous, sub-internal limiting membrane, and/or submacular hemorrhage removal associated with ruptured retinal arterial macroaneurysms.

Hideo Nakamura1, Kazuhisa Hayakawa, Shoichi Sawaguchi, Takeshi Gaja, Noriyoshi Nagamine, Kodo Medoruma.   

Abstract

BACKGROUND: Ruptured retinal arterial macroaneurysms (RAM) can bleed into the various spaces of the eye. The hemorrhage of the inner layer conceals hemorrhage of the outer layer, making it difficult to diagnose the distribution of hemorrhage accurately and to predict the prognosis in clinical examinations. The objective of this study was to examine the clinical features and prognosis of ruptured RAM on the basis of surgical observations.
METHODS: Retrospective review of 33 eyes of 31 patients with impairment of visual acuity due to hemorrhage from a ruptured RAM, who had undergone pars plana vitrectomy. A study of the location of hemorrhage was made from the preoperative fundus photographs and video of the surgical procedure.
RESULTS: Hemorrhage from the RAM was present in two or more locations, consisting of the vitreous cavity, beneath the internal limiting membrane (sub-ILM), or the subretinal space in all but one eye. Sub-ILM hemorrhage was presented in the macular region in 22 of the 27 eyes presenting with sub-ILM hemorrhage (81%). Submacular hemorrhage was only detected when sub-ILM hemorrhage removed during surgery in 12 of the 22 eyes (55%) with sub-ILM hemorrhage. The preoperative VA ranged from hand motion to 0.1, while postoperative VA improved 0.01 to 1.0 (average: 0.2, paired t-test, P<0.01). The VA was poor in eyes with dense submacular hemorrhage, while it was good in eyes with other hemorrhage.
CONCLUSIONS: The effects of vitrectomy were influenced by the location of hemorrhage from the RAM. The VA was poor in eyes exhibiting dense submacular hemorrhage. However, since hemorrhage from a RAM was present at various levels within the eye, it was difficult to evaluate the amount of submacular hemorrhage prior to surgery.

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Year:  2007        PMID: 18071732     DOI: 10.1007/s00417-007-0724-0

Source DB:  PubMed          Journal:  Graefes Arch Clin Exp Ophthalmol        ISSN: 0721-832X            Impact factor:   3.117


  21 in total

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Journal:  Am J Ophthalmol       Date:  2003-04       Impact factor: 5.258

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Journal:  Am J Ophthalmol       Date:  1982-12       Impact factor: 5.258

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  7 in total

1.  [Spontaneous macula hemorrhage. Subhyaloid/sub-inner limiting membrane (ILM)].

Authors:  D Völcker; B Junker; L L Hansen
Journal:  Ophthalmologe       Date:  2012-07       Impact factor: 1.059

2.  Recombinant tissue plasminogen activator, vitrectomy, and gas for recent submacular hemorrhage displacement due to retinal macroaneurysm.

Authors:  Elsbeth J T van Zeeburg; Matteo G Cereda; Jan C van Meurs
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2012-08-04       Impact factor: 3.117

3.  Angiographic features and disease outcomes of symptomatic retinal arterial macroaneurysms.

Authors:  Emily L Hughes; Ian J Dooley; Kevin P Kennelly; Fergus Doyle; W F Siah; P Connell
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2016-05-25       Impact factor: 3.117

4.  Intraoperative optical coherence tomography-guided subretinal cocktail injection in a case of ruptured retinal artery macro-aneurysm with multilevel bleed.

Authors:  Atul Kumar; M Dheepak Sundar; Rohan Chawla; Divya Agarwal; Nasiq Hasan
Journal:  Indian J Ophthalmol       Date:  2020-07       Impact factor: 1.848

5.  Intravitreal r-tPA Injection and Pneumatic Displacement for Submacular Retinal Hemorrhage: A Case Series.

Authors:  Filippo Confalonieri; Ingar Stene-Johansen; Xhevat Lumi; Goran Petrovski
Journal:  Case Rep Ophthalmol       Date:  2022-08-16

6.  Vitreous hemorrhage caused by ruptured retinal macroaneurysm.

Authors:  Kazunobu Asao; Atsuko Nakada; Yoshimi Kawasaki
Journal:  Case Rep Ophthalmol       Date:  2014-02-01

Review 7.  Traumatic submacular hemorrhage: available treatment options and synthesis of the literature.

Authors:  Giamberto Casini; Pasquale Loiudice; Martina Menchini; Francesco Sartini; Stefano De Cillà; Michele Figus; Marco Nardi
Journal:  Int J Retina Vitreous       Date:  2019-12-11
  7 in total

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