Literature DB >> 18071591

Synthesis of a quaternary polyprenyl ammonium salt.

Olga V Sizova1, Natalia S Utkina, Nadezhda A Kalinchuk, Leonid L Danilov, Sergey D Maltsev.   

Abstract

Reaction of primary C(55)-allylic alcohol moraprenol (WT(3)C(7-9)-OH, a polyprenol from mulberry leaves) with triethylamine in the presence of phosphorus oxychloride leads to a quaternary ammonium chloride with a good yield (72%) and high cis-stereoselectivity of the terminal isoprene unit. Cationic polyprenyl derivatives may be useful for transfection and immunological studies.

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Year:  2007        PMID: 18071591

Source DB:  PubMed          Journal:  Acta Biochim Pol        ISSN: 0001-527X            Impact factor:   2.149


  2 in total

1.  Application of supercritical CO2 for extraction of polyisoprenoid alcohols and their esters from plant tissues.

Authors:  Adam Jozwiak; Robert Brzozowski; Zygmunt Bujnowski; Tadeusz Chojnacki; Ewa Swiezewska
Journal:  J Lipid Res       Date:  2013-05-14       Impact factor: 5.922

2.  Antibacterial, cytotoxic and genotoxic activity of nitrogenated and haloid derivatives of C50-C60 and C70-C120 polyprenol homologs.

Authors:  Ran Tao; Cheng-Zhang Wang; Jian-Zhong Ye; Hao Zhou; Hong-Xia Chen; Chang-Wei Zhang
Journal:  Lipids Health Dis       Date:  2016-10-10       Impact factor: 3.876

  2 in total

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