Literature DB >> 18071115

Long-term risk of recurrence after intact excision of pleomorphic adenomas of the lacrimal gland.

Zanna I Currie1, Geoffrey E Rose.   

Abstract

OBJECTIVE: To ascertain the need for follow-up after excision of pleomorphic adenoma of the lacrimal gland.
METHODS: Medical records were reviewed for 133 patients and only those patients with 5 years or more of follow up were classified into the following 5 subgroups: those with intact excision (group IA, n = 46), those with surgically intact excision but areas of complete attenuation of the pseudocapsule at histologic analysis (group IB, n = 7), those with previous inadvertent incisional biopsy (group IIA, n = 9), those with breach of the pseudocapsule during attempted intact excision (group IIB, n = 5), and those undergoing definitive surgery because of tumor recurrence after previous incomplete excision (group III, n = 5).
RESULTS: Seventy-two patients were followed up longer than 5 years; there were no known tumor recurrences among 61 patients excluded with shorter follow-up. Patients in groups IA and IB exhibited no tumor recurrences at 8.2 to 34.1 years of follow-up. A benign recurrence occurred along the superior orbital fissure in 1 patient in group IIA 12(1/2) years after the initial surgery and was resected. There were no recurrences in patients in groups IIB or III.
CONCLUSIONS: Discharge would seem justified after intact excision of lacrimal gland pleomorphic adenoma, even when histologic examination shows extreme attenuation of the pseudocapsule. Long-term follow-up is, however, necessary when there has been tumor disruption, either inadvertently during previous biopsy or by capsular breach during definitive excision.

Entities:  

Mesh:

Year:  2007        PMID: 18071115     DOI: 10.1001/archopht.125.12.1643

Source DB:  PubMed          Journal:  Arch Ophthalmol        ISSN: 0003-9950


  7 in total

1.  Accuracy of fine needle aspiration biopsy processed by cytologic smear and cell block techniques for the diagnosis of lacrimal gland tumors: a study of 48 cases.

Authors:  Xiangning Wang; Jiang Qian; Yifei Yuan; Bo Ping; Liqing Feng; Yingwen Bi; Xiaping Li
Journal:  Int J Clin Exp Pathol       Date:  2014-06-15

2.  Masses of the Lacrimal Gland: Evaluation and Treatment.

Authors:  Jane S Kim; Jason Liss
Journal:  J Neurol Surg B Skull Base       Date:  2021-02-18

3.  Primary Malignant Orbital Tumors.

Authors:  Jacquelyn Laplant; Kimberly Cockerham
Journal:  J Neurol Surg B Skull Base       Date:  2021-02-18

4.  Stereotactic radiosurgery for recurrent pleomorphic adenoma of the lacrimal gland: a case report.

Authors:  Motoyuki Umekawa; Keita Saito; Yuki Shinya; Hirotaka Hasegawa; Mariko Kawashima; Yu Teranishi; Atsuto Katano; Masako Ikemura; Nobuhito Saito
Journal:  Acta Neurochir (Wien)       Date:  2022-10-15       Impact factor: 2.816

5.  Multifocal recurrence of pleomorphic adenoma of the lacrimal gland.

Authors:  Jiawei Zhao; Alexandra M Papp; Michelle D Williams; J Matthew Debnam; Bita Esmaeli
Journal:  Am J Ophthalmol Case Rep       Date:  2022-05-27

6.  Epithelial Lacrimal Gland Tumours in Nigeria: Clinicopathological Features and Treatment.

Authors:  Oluyemi Fasina; Adewunmi Oluseye Adeoye; Olanipekun Olalekan Aremu
Journal:  J West Afr Coll Surg       Date:  2022-03-26

Review 7.  Pleomorphic adenoma of the lacrimal gland: A review with updates on malignant transformation and molecular genetics.

Authors:  William Harrison; Patricia Pittman; Thomas Cummings
Journal:  Saudi J Ophthalmol       Date:  2018-03-02
  7 in total

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