Literature DB >> 18071076

Which hospitals have significantly better or worse than expected mortality rates for acute myocardial infarction patients? Improved risk adjustment with present-at-admission diagnoses.

George J Stukenborg1, Douglas P Wagner, Frank E Harrell, M Norman Oliver, Steven W Heim, Amy L Price, Caroline Kim Han, Andrew M D Wolf, Alfred F Connors.   

Abstract

BACKGROUND: Public reports that compare hospital mortality rates for patients with acute myocardial infarction are commonly used strategies for improving the quality of care delivered to these patients. Fair comparisons of hospital mortality rates require thorough adjustments for differences among patients in baseline mortality risk. This study examines the effect on hospital mortality rate comparisons of improved risk adjustment methods using diagnoses reported as present-at-admission. METHODS AND
RESULTS: Logistic regression models and related methods originally used by California to compare hospital mortality rates for patients with acute myocardial infarction are replicated. These results are contrasted with results obtained for the same hospitals by patient-level mortality risk adjustment models using present-at-admission diagnoses, using 3 statistical methods of identifying hospitals with higher or lower than expected mortality: indirect standardization, adjusted odds ratios, and hierarchical models. Models using present-at-admission diagnoses identified substantially fewer hospitals as outliers than did California model A for each of the 3 statistical methods considered.
CONCLUSIONS: Large improvements in statistical performance can be achieved with the use of present-at-admission diagnoses to characterize baseline mortality risk. These improvements are important because models with better statistical performance identify different hospitals as having better or worse than expected mortality.

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Year:  2007        PMID: 18071076     DOI: 10.1161/CIRCULATIONAHA.107.712323

Source DB:  PubMed          Journal:  Circulation        ISSN: 0009-7322            Impact factor:   29.690


  4 in total

1.  Racial differences in mortality among patients with acute ischemic stroke: an observational study.

Authors:  Ying Xian; Robert G Holloway; Katia Noyes; Manish N Shah; Bruce Friedman
Journal:  Ann Intern Med       Date:  2011-02-01       Impact factor: 25.391

2.  Hospital-level associations with 30-day patient mortality after cardiac surgery: a tutorial on the application and interpretation of marginal and multilevel logistic regression.

Authors:  Masoumeh Sanagou; Rory Wolfe; Andrew Forbes; Christopher Michael Reid
Journal:  BMC Med Res Methodol       Date:  2012-03-12       Impact factor: 4.615

3.  Derivation and validation of a risk adjustment model for predicting seven day mortality in emergency medical admissions: mixed prospective and retrospective cohort study.

Authors:  Steve Goodacre; Richard Wilson; Neil Shephard; Jon Nicholl
Journal:  BMJ       Date:  2012-05-01

4.  Statistical profiling of hospital performance using acute coronary syndrome mortality.

Authors:  S O Manda; C P Gale; A S Hall; M S Gilthorpe
Journal:  Cardiovasc J Afr       Date:  2012-11       Impact factor: 1.167

  4 in total

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