Literature DB >> 18070838

The neuroendocrine effects of traumatic brain injury.

Micol S Rothman1, David B Arciniegas, Christopher M Filley, Margaret E Wierman.   

Abstract

Neuroendocrine dysfunction after traumatic brain injury (TBI) is under-diagnosed, under-treated, and may adversely affect the rate of recovery. Single or multiple pituitary-target hormone disruption occurs in up to two-thirds of persons with TBI, most commonly affecting the gonadal and growth hormone axes. The time course of decline in and recovery of pituitary function in relation to cognitive dysfunction and rehabilitation progress are not well described. This article reviews the clinical spectrum of neuroendocrine deficits after TBI and their underlying mechanisms. Future studies of the effects of hormonal replacement on recovery are recommended.

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Year:  2007        PMID： 18070838     DOI： 10.1176/jnp.2007.19.4.363

Source DB:  PubMed          Journal:  J Neuropsychiatry Clin Neurosci        ISSN： 0895-0172            Impact factor:   2.198


  15 in total

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3.  Neuropsychological recovery and quality-of-life in children and adolescents with growth hormone deficiency following TBI: a preliminary study.

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Review 4.  Mood disorders after TBI.

Authors:  Ricardo E Jorge; David B Arciniegas
Journal:  Psychiatr Clin North Am       Date:  2014-01-14

Review 5.  Female hypogonadism: evaluation of the hypothalamic-pituitary-ovarian axis.

Authors:  Micol S Rothman; Margaret E Wierman
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7.  Chronic Repetitive Mild Traumatic Brain Injury Results in Reduced Cerebral Blood Flow, Axonal Injury, Gliosis, and Increased T-Tau and Tau Oligomers.

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8.  Changes and effects of plasma arginine vasopressin in traumatic brain injury.

Authors:  W D Huang; J Pan; M Xu; W Su; Y Q Lu; Z J Chen; T Y Jiang; Y M Yang
Journal:  J Endocrinol Invest       Date:  2008-11       Impact factor: 4.256

Review 9.  Addressing neuropsychiatric disturbances during rehabilitation after traumatic brain injury: current and future methods.

Authors:  David B Arciniegas
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Journal:  Front Aging Neurosci       Date:  2015-02-18       Impact factor: 5.750
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