Literature DB >> 18069854

Synthesis and structural revision of (+/-)-laurentristich-4-ol.

Pinhong Chen1, Junhua Wang, Kun Liu, Chaozhong Li.   

Abstract

The structure of tetracyclic natural sesquiterpene laurentristich-4-ol was revised based on its synthetic studies. The proposed and the revised structures of laurentristich-4-ol were both synthesized with SmI(2)-mediated ketyl radical cyclization as the key step to construct the spirocyclic ether skeleton.

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Year:  2007        PMID: 18069854     DOI: 10.1021/jo7021247

Source DB:  PubMed          Journal:  J Org Chem        ISSN: 0022-3263            Impact factor:   4.354


  3 in total

Review 1.  Survey of marine natural product structure revisions: a synergy of spectroscopy and chemical synthesis.

Authors:  Takashi L Suyama; William H Gerwick; Kerry L McPhail
Journal:  Bioorg Med Chem       Date:  2011-06-12       Impact factor: 3.641

Review 2.  Samarium diiodide mediated reactions in total synthesis.

Authors:  K C Nicolaou; Shelby P Ellery; Jason S Chen
Journal:  Angew Chem Int Ed Engl       Date:  2009       Impact factor: 15.336

3.  Novel benzofuran derivative DK-1014 attenuates lung inflammation via blocking of MAPK/AP-1 and AKT/mTOR signaling in vitro and in vivo.

Authors:  Xuezhen Xu; Ok-Kyoung Kwon; In-Sik Shin; Jyotirling R Mali; Dipesh S Harmalkar; Yourim Lim; Gilhye Lee; Qili Lu; Sei-Ryang Oh; Kyung-Seop Ahn; Hye-Gwang Jeong; Kyeong Lee
Journal:  Sci Rep       Date:  2019-01-29       Impact factor: 4.379

  3 in total

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