Literature DB >> 18069841

Preparation of fully substituted anilines for the synthesis of functionalized indoles.

Armin H Stoll1, Paul Knochel.   

Abstract

A wide range of highly functionalized indoles were prepared by the successive magnesiation of readily available o-alkynyl protected anilines using TMPMgCl.LiCl or LDA, followed by a KH-mediated cyclization reaction.

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Year:  2007        PMID： 18069841     DOI： 10.1021/ol7025872

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  4 in total

1.  Synthesis of diverse indole libraries on polystyrene resin - Scope and limitations of an organometallic reaction on solid supports.

Authors:  Kerstin Knepper; Sylvia Vanderheiden; Stefan Bräse
Journal:  Beilstein J Org Chem       Date:  2012-07-26       Impact factor: 2.883

2.  Functionalization of heterocyclic compounds using polyfunctional magnesium and zinc reagents.

Authors:  Paul Knochel; Matthias A Schade; Sebastian Bernhardt; Georg Manolikakes; Albrecht Metzger; Fabian M Piller; Christoph J Rohbogner; Marc Mosrin
Journal:  Beilstein J Org Chem       Date:  2011-09-13       Impact factor: 2.883

3.  Disposable cartridge concept for the on-demand synthesis of turbo Grignards, Knochel-Hauser amides, and magnesium alkoxides.

Authors:  Mateo Berton; Kevin Sheehan; Andrea Adamo; D Tyler McQuade
Journal:  Beilstein J Org Chem       Date:  2020-06-19       Impact factor: 2.883

4.  Structural tracking of the potassium-mediated magnesiation of anisole.

Authors:  William Clegg; Ben Conway; Pablo García-Alvarez; Alan R Kennedy; Robert E Mulvey; Luca Russo; Jörg Sassmannshausen; Tell Tuttle
Journal:  Chemistry       Date:  2009-10-19       Impact factor: 5.236
  4 in total

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