Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Eukaryotic initiation factor 4E.

Literature DB >> 18069043

Eukaryotic initiation factor 4E.

Abstract

Eukaryotic translation initiation factor 4E (eIF4E) is perhaps best known for its function in the initiation of protein synthesis on capped mRNAs in the cytoplasm. However, recent studies have highlighted that eIF4E has many additional functions, which include the nuclear export of specific mRNAs as well as roles in ageing and the translation of some uncapped viral RNAs. This review aims to update the reader on recent developments, including the potential of eIF4E as a therapeutic target.

Entities: Chemical

Mesh：

Substances：

Year: 2007 PMID： 18069043 PMCID： PMC3061223 DOI： 10.1016/j.biocel.2007.10.023

Source DB: PubMed Journal: Int J Biochem Cell Biol ISSN： 1357-2725 Impact factor: 5.085

23 in total

1. Hierarchical phosphorylation of the translation inhibitor 4E-BP1.

Authors: A C Gingras; B Raught; S P Gygi; A Niedzwiecka; M Miron; S K Burley; R D Polakiewicz; A Wyslouch-Cieszynska; R Aebersold; N Sonenberg
Journal: Genes Dev Date: 2001-11-01 Impact factor: 11.361

Review 2. The role of c-myc in regulation of translation initiation.

Authors: Emmett V Schmidt
Journal: Oncogene Date: 2004-04-19 Impact factor: 9.867

Review 3. Controlling gene expression through RNA regulons: the role of the eukaryotic translation initiation factor eIF4E.

Authors: Biljana Culjkovic; Ivan Topisirovic; Katherine L B Borden
Journal: Cell Cycle Date: 2007-01-11 Impact factor: 4.534

4. Eukaryotic translation initiation factor 4E is a cellular target for toxicity and death due to exposure to cadmium chloride.

Authors: Sreekumar Othumpangat; Michael Kashon; Pius Joseph
Journal: J Biol Chem Date: 2005-05-05 Impact factor: 5.157

Review 5. Role and fate of PML nuclear bodies in response to interferon and viral infections.

Authors: T Regad; M K Chelbi-Alix
Journal: Oncogene Date: 2001-10-29 Impact factor: 9.867

6. Activation of the translational suppressor 4E-BP1 following infection with encephalomyocarditis virus and poliovirus.

Authors: A C Gingras; Y Svitkin; G J Belsham; A Pause; N Sonenberg
Journal: Proc Natl Acad Sci U S A Date: 1996-05-28 Impact factor: 11.205

7. Human eukaryotic translation initiation factor 4G (eIF4G) recruits mnk1 to phosphorylate eIF4E.

Authors: S Pyronnet; H Imataka; A C Gingras; R Fukunaga; T Hunter; N Sonenberg
Journal: EMBO J Date: 1999-01-04 Impact factor: 11.598

8. eIF4E--from translation to transformation.

Authors: Yaël Mamane; Emmanuel Petroulakis; Liwei Rong; Kaori Yoshida; Lian Wee Ler; Nahum Sonenberg
Journal: Oncogene Date: 2004-04-19 Impact factor: 9.867

9. Aberrant eukaryotic translation initiation factor 4E-dependent mRNA transport impedes hematopoietic differentiation and contributes to leukemogenesis.

Authors: Ivan Topisirovic; Monica L Guzman; Melanie J McConnell; Jonathan D Licht; Biljana Culjkovic; Sarah J Neering; Craig T Jordan; Katherine L B Borden
Journal: Mol Cell Biol Date: 2003-12 Impact factor: 4.272

Review 10. Does phosphorylation of the cap-binding protein eIF4E play a role in translation initiation?

Authors: Gert C Scheper; Christopher G Proud
Journal: Eur J Biochem Date: 2002-11

28 in total

1. Protein phosphatase 2A negatively regulates eukaryotic initiation factor 4E phosphorylation and eIF4F assembly through direct dephosphorylation of Mnk and eIF4E.

Authors: Yikun Li; Ping Yue; Xingming Deng; Takeshi Ueda; Rikiro Fukunaga; Fadlo R Khuri; Shi-Yong Sun
Journal: Neoplasia Date: 2010-10 Impact factor: 5.715

Review 2. Eukaryotic translation initiation factor 4E-mediated recessive resistance to plant viruses and its utility in crop improvement.

Authors: Aiming Wang; Sowmya Krishnaswamy
Journal: Mol Plant Pathol Date: 2012-03-02 Impact factor: 5.663

3. Expression of Plakophilins (PKP1, PKP2, and PKP3) in breast cancers.

Authors: Guzin Gonullu Demirag; Yurdanur Sullu; Idris Yucel
Journal: Med Oncol Date: 2011-09-25 Impact factor: 3.064

4. The eIF4E/eIF4G interaction inhibitor 4EGI-1 augments TRAIL-mediated apoptosis through c-FLIP Down-regulation and DR5 induction independent of inhibition of cap-dependent protein translation.

Authors: Songqing Fan; Yikun Li; Ping Yue; Fadlo R Khuri; Shi-Yong Sun
Journal: Neoplasia Date: 2010-04 Impact factor: 5.715

5. Functional characterization of the translation initiation factor eIF4E of Echinococcus granulosus.

Authors: Filipe Santos Pereira-Dutra; Martin Cancela; Bruna Valandro Meneghetti; Henrique Bunselmeyer Ferreira; Karina Mariante Monteiro; Arnaldo Zaha
Journal: Parasitol Res Date: 2019-08-10 Impact factor: 2.289

6. Common EIF4E variants modulate risk for autism spectrum disorders in the high-functioning range.

Authors: Regina Waltes; Johannes Gfesser; Denise Haslinger; Katja Schneider-Momm; Monica Biscaldi; Anette Voran; Christine M Freitag; Andreas G Chiocchetti
Journal: J Neural Transm (Vienna) Date: 2014-05-13 Impact factor: 3.575

7. A mammalian pre-mRNA 5' end capping quality control mechanism and an unexpected link of capping to pre-mRNA processing.

Authors: Xinfu Jiao; Jeong Ho Chang; Turgay Kilic; Liang Tong; Megerditch Kiledjian
Journal: Mol Cell Date: 2013-03-21 Impact factor: 17.970