Literature DB >> 18068725

Probing reward function in posttraumatic stress disorder: expectancy and satisfaction with monetary gains and losses.

James W Hopper1, Roger K Pitman, Zhaohui Su, Gene M Heyman, Natasha B Lasko, Michael L Macklin, Scott P Orr, Scott E Lukas, Igor Elman.   

Abstract

BACKGROUND: Posttraumatic stress disorder (PTSD) may be associated with dysfunctional reward processing. The present study assessed for such dysfunction in both the expectancy and outcome phases of reward processing.
METHODS: Male Vietnam veterans with (n=15) and without (n=11) combat-related PTSD were administered a wheel of fortune-type gambling task. Self-reported ratings of expectancy and satisfaction were collected respectively before and after each experience of monetary gain or loss.
RESULTS: PTSD participants reported both lower expectancy of reward and lower satisfaction with reward when it was received. The latter result was manifest in a failure of PTSD participants to show the greater satisfaction that normally accompanies rewards received under conditions of low expectancy.
CONCLUSION: These results suggest reward function impairment in PTSD related to expectancy, satisfaction, and the expectancy-satisfaction relationship.

Entities:  

Mesh:

Year:  2008        PMID: 18068725      PMCID: PMC2551554          DOI: 10.1016/j.jpsychires.2007.10.008

Source DB:  PubMed          Journal:  J Psychiatr Res        ISSN: 0022-3956            Impact factor:   4.791


  34 in total

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